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Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt.
Gege, Christian; Albers, Michael; Kinzel, Olaf; Kleymann, Gerald; Schlüter, Thomas; Steeneck, Christoph; Hoffmann, Thomas; Xue, Xiaohua; Cummings, Maxwell D; Spurlino, John; Milligan, Cynthia; Fourie, Anne M; Edwards, James P; Leonard, Kristi; Coe, Kevin; Scott, Brian; Pippel, Dan; Goldberg, Steven D.
Afiliación
  • Gege C; Phenex Pharmaceuticals AG, Waldhofer Strasse 104, 69123 Heidelberg, Germany. Electronic address: christian.gege@web.de.
  • Albers M; Phenex Pharmaceuticals AG, Waldhofer Strasse 104, 69123 Heidelberg, Germany.
  • Kinzel O; Phenex Pharmaceuticals AG, Waldhofer Strasse 104, 69123 Heidelberg, Germany.
  • Kleymann G; Phenex Pharmaceuticals AG, Waldhofer Strasse 104, 69123 Heidelberg, Germany.
  • Schlüter T; Phenex Pharmaceuticals AG, Waldhofer Strasse 104, 69123 Heidelberg, Germany.
  • Steeneck C; Phenex Pharmaceuticals AG, Waldhofer Strasse 104, 69123 Heidelberg, Germany.
  • Hoffmann T; Phenex Pharmaceuticals AG, Waldhofer Strasse 104, 69123 Heidelberg, Germany.
  • Xue X; Janssen Research and Development, LLC, San Diego, CA 92121, USA.
  • Cummings MD; Janssen Research and Development, Spring House, PA 19477, USA.
  • Spurlino J; Janssen Research and Development, Spring House, PA 19477, USA.
  • Milligan C; Janssen Research and Development, Spring House, PA 19477, USA.
  • Fourie AM; Janssen Research and Development, LLC, San Diego, CA 92121, USA.
  • Edwards JP; Janssen Research and Development, LLC, San Diego, CA 92121, USA.
  • Leonard K; Janssen Research and Development, Spring House, PA 19477, USA.
  • Coe K; Janssen Research and Development, LLC, San Diego, CA 92121, USA.
  • Scott B; Janssen Research and Development, LLC, San Diego, CA 92121, USA.
  • Pippel D; Janssen Research and Development, LLC, San Diego, CA 92121, USA.
  • Goldberg SD; Janssen Research and Development, LLC, San Diego, CA 92121, USA. Electronic address: sgoldbe1@its.jnj.com.
Bioorg Med Chem Lett ; 30(12): 127205, 2020 06 15.
Article en En | MEDLINE | ID: mdl-32336498
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiazoles / Bibliotecas de Moléculas Pequeñas / Miembro 3 del Grupo F de la Subfamilia 1 de Receptores Nucleares / Amidas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiazoles / Bibliotecas de Moléculas Pequeñas / Miembro 3 del Grupo F de la Subfamilia 1 de Receptores Nucleares / Amidas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article