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Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism.
Yu, Xia; Gao, Xiaopan; Zhu, Kaixiang; Yin, Han; Mao, Xujian; Wojdyla, Justyna Aleksandra; Qin, Bo; Huang, Hairong; Wang, Meitian; Sun, Yi-Cheng; Cui, Sheng.
Afiliación
  • Yu X; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Gao X; National Clinical Laboratory on Tuberculosis, Beijing Key Laboratory for Drug-Resistant Tuberculosis Research Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, 101149, Beijing, China.
  • Zhu K; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. panda888@ipbcams.ac.cn.
  • Yin H; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Mao X; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Wojdyla JA; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Qin B; Swiss Light Source at the Paul Scherrer Institute, CH-5232, Villigen, Switzerland.
  • Huang H; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Wang M; National Clinical Laboratory on Tuberculosis, Beijing Key Laboratory for Drug-Resistant Tuberculosis Research Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, 101149, Beijing, China.
  • Sun YC; Swiss Light Source at the Paul Scherrer Institute, CH-5232, Villigen, Switzerland.
  • Cui S; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. Sunyc@ipbcams.ac.cn.
Commun Biol ; 3(1): 216, 2020 05 07.
Article en En | MEDLINE | ID: mdl-32382148

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Toxinas Bacterianas / Antitoxinas / Sistemas Toxina-Antitoxina / Mycobacterium tuberculosis Idioma: En Revista: Commun Biol Año: 2020 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Toxinas Bacterianas / Antitoxinas / Sistemas Toxina-Antitoxina / Mycobacterium tuberculosis Idioma: En Revista: Commun Biol Año: 2020 Tipo del documento: Article País de afiliación: China