Ultrasensitive detection of microRNA based on a homogeneous label-free electrochemical platform using G-triplex/methylene blue as a signal generator.

Zhao, Ling-Li; Pan, Hui-Yu; Zhang, Xin-Xiang; Zhou, Ying-Lin

Zhao, Ling-Li; Pan, Hui-Yu; Zhang, Xin-Xiang; Zhou, Ying-Lin.

Afiliación

Zhao LL; Beijing National Laboratory for Molecular Sciences (BNLMS), MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Pan HY; Beijing National Laboratory for Molecular Sciences (BNLMS), MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Zhang XX; Beijing National Laboratory for Molecular Sciences (BNLMS), MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Zhou YL; Beijing National Laboratory for Molecular Sciences (BNLMS), MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China. Electronic address: zhouyl@pku.edu.cn.

Anal Chim Acta ; 1116: 62-69, 2020 Jun 15.

Article en En | MEDLINE | ID: mdl-32389190

Asunto(s)

Técnicas Biosensibles/métodos; ADN/química; Técnicas Electroquímicas/métodos; Azul de Metileno/química; MicroARNs/análisis; Células A549; ADN/genética; Humanos; Límite de Detección; MicroARNs/genética; Técnicas de Amplificación de Ácido Nucleico/métodos; Conformación de Ácido Nucleico; Hibridación de Ácido Nucleico; Prueba de Estudio Conceptual

Palabras clave

G-triplex DNA; Homogeneous electrochemical biosensor; Isothermal exponential amplification; Label-free; MicroRNA

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ADN / Técnicas Biosensibles / MicroARNs / Técnicas Electroquímicas / Azul de Metileno Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Anal Chim Acta Año: 2020 Tipo del documento: Article País de afiliación: China

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