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Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent.
Mazzoni, Alessio; Salvati, Lorenzo; Maggi, Laura; Capone, Manuela; Vanni, Anna; Spinicci, Michele; Mencarini, Jessica; Caporale, Roberto; Peruzzi, Benedetta; Antonelli, Alberto; Trotta, Michele; Zammarchi, Lorenzo; Ciani, Luca; Gori, Leonardo; Lazzeri, Chiara; Matucci, Andrea; Vultaggio, Alessandra; Rossi, Oliviero; Almerigogna, Fabio; Parronchi, Paola; Fontanari, Paolo; Lavorini, Federico; Peris, Adriano; Rossolini, Gian Maria; Bartoloni, Alessandro; Romagnani, Sergio; Liotta, Francesco; Annunziato, Francesco; Cosmi, Lorenzo.
Afiliación
  • Mazzoni A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Salvati L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Maggi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Capone M; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Vanni A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Spinicci M; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Mencarini J; Infectious and Tropical Diseases Unit.
  • Caporale R; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Peruzzi B; Infectious and Tropical Diseases Unit.
  • Antonelli A; Flow Cytometry Diagnostic Center and Immunotherapy (CDCI).
  • Trotta M; Flow Cytometry Diagnostic Center and Immunotherapy (CDCI).
  • Zammarchi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Ciani L; Infectious and Tropical Diseases Unit.
  • Gori L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Lazzeri C; Infectious and Tropical Diseases Unit.
  • Matucci A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Vultaggio A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Rossi O; Intensive Care Unit and Regional Extracorporeal Membrane Oxygenation (ECMO) Referral Centre.
  • Almerigogna F; Immunoallergology Unit.
  • Parronchi P; Immunoallergology Unit.
  • Fontanari P; Immunoallergology Unit.
  • Lavorini F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Peris A; Immunoallergology Unit.
  • Rossolini GM; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Bartoloni A; Immunology and Cell Therapy Unit.
  • Romagnani S; Cardiac Anesthesia and Intensive Care Unit.
  • Liotta F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Annunziato F; Pneumology and Intensive Care Unit, and.
  • Cosmi L; Intensive Care Unit and Regional Extracorporeal Membrane Oxygenation (ECMO) Referral Centre.
J Clin Invest ; 130(9): 4694-4703, 2020 09 01.
Article en En | MEDLINE | ID: mdl-32463803
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neumonía Viral / Interleucina-6 / Infecciones por Coronavirus / Citotoxicidad Inmunológica / Betacoronavirus Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Invest Año: 2020 Tipo del documento: Article País de afiliación: Italia
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neumonía Viral / Interleucina-6 / Infecciones por Coronavirus / Citotoxicidad Inmunológica / Betacoronavirus Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Invest Año: 2020 Tipo del documento: Article País de afiliación: Italia