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Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination.
Choi, Yoonjoo; Jeong, Sukyo; Choi, Jung-Min; Ndong, Christian; Griswold, Karl E; Bailey-Kellogg, Chris; Kim, Hak-Sung.
Afiliación
  • Choi Y; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea.
  • Jeong S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea.
  • Choi JM; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea.
  • Ndong C; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, United States of America.
  • Griswold KE; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, United States of America.
  • Bailey-Kellogg C; Norris Cotton Cancer Center at Dartmouth, Lebanon, New Hampshire, United States of America.
  • Kim HS; Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire, United States of America.
PLoS Comput Biol ; 16(8): e1008150, 2020 08.
Article en En | MEDLINE | ID: mdl-32866140
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2020 Tipo del documento: Article