Overall hemostasis potential and aPTT-clot waveform analysis as powerful laboratory diagnostic tools for identification of hemophilia A patients with unexpected bleeding phenotype.

Milos, Marija; Coen Herak, Désirée; Mahmoud Hourani Soutari, Nida; Pavic, Josipa; Zupancic-Salek, Silva; Zadro, Renata; Antovic, Jovan P

Milos, Marija; Coen Herak, Désirée; Mahmoud Hourani Soutari, Nida; Pavic, Josipa; Zupancic-Salek, Silva; Zadro, Renata; Antovic, Jovan P.

Afiliación

Milos M; Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Zagreb, Croatia.
Coen Herak D; Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Zagreb, Croatia.
Mahmoud Hourani Soutari N; Department of Coagulation Research, Institute for Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Pavic J; Department of Clinical Chemistry, Karolinska University Hospital, Stockholm, Sweden.
Zupancic-Salek S; Department of Medical Biochemistry and Hematology Laboratory, General County Hospital Livno, Livno, Bosnia and Herzegovina.
Zadro R; Department of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia.
Antovic JP; St. Catherine Specialty Hospital, Zabok, Croatia.

Int J Lab Hematol ; 43(2): 273-280, 2021 Apr.

Article en En | MEDLINE | ID: mdl-32964648

Asunto(s)

Coagulación Sanguínea; Hemofilia A/sangre; Hemofilia A/complicaciones; Hemorragia/diagnóstico; Hemorragia/etiología; Hemostasis; Tiempo de Tromboplastina Parcial; Adolescente; Adulto; Anciano; Estudios de Casos y Controles; Manejo de la Enfermedad; Susceptibilidad a Enfermedades; Factor VIII; Femenino; Humanos; Masculino; Persona de Mediana Edad; Tiempo de Tromboplastina Parcial/métodos; Tiempo de Tromboplastina Parcial/normas; Fenotipo; Índice de Severidad de la Enfermedad; Trombina/metabolismo; Adulto Joven

Palabras clave

aPTT-clot waveform analysis; bleeding phenotype; endogenous thrombin potential; hemophilia A; overall hemostasis potential

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiempo de Tromboplastina Parcial / Coagulación Sanguínea / Hemofilia A / Hemorragia / Hemostasis Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Lab Hematol Asunto de la revista: HEMATOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Croacia

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