Development of HPLC Method for Quantification of Sinigrin from <i>Raphanus sativus</i> Roots and Evaluation of Its Anticancer Potential.

Nair, Anroop B; Gandhi, Dipal; Patel, Snehal S; Morsy, Mohamed A; Gorain, Bapi; Attimarad, Mahesh; Shah, Jigar N

Development of HPLC Method for Quantification of Sinigrin from Raphanus sativus Roots and Evaluation of Its Anticancer Potential.

Nair, Anroop B; Gandhi, Dipal; Patel, Snehal S; Morsy, Mohamed A; Gorain, Bapi; Attimarad, Mahesh; Shah, Jigar N.

Afiliación

Nair AB; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Gandhi D; Department of Pharmacognosy, Institute of Pharmacy, Nirma University, Ahmedabad 382481, Gujarat, India.
Patel SS; Department of Pharmacology, Institute of Pharmacy, Nirma University, Ahmedabad 382481, Gujarat, India.
Morsy MA; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Gorain B; Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia 61511, Egypt.
Attimarad M; School of Pharmacy, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Selangor 47500, Malaysia.
Shah JN; Centre for Drug Delivery and Molecular Pharmacology, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Selangor 47500, Malaysia.

Molecules ; 25(21)2020 Oct 26.

Article en En | MEDLINE | ID: mdl-33114598

Asunto(s)

Antineoplásicos/análisis; Antineoplásicos/farmacología; Cromatografía Líquida de Alta Presión/métodos; Glucosinolatos/análisis; Glucosinolatos/farmacología; Raíces de Plantas/química; Raphanus/química; Línea Celular Tumoral; Cromatografía de Fase Inversa; Humanos; Modelos Lineales

Palabras clave

RP-HPLC; Sinigrin; apoptosis; caspase-3; cytotoxicity; method validation; quantification

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Líquida de Alta Presión / Raíces de Plantas / Raphanus / Glucosinolatos / Antineoplásicos Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Arabia Saudita

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