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Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease.
Caliez, Julien; Riou, Marianne; Manaud, Grégoire; Nakhleh, Morad K; Quatredeniers, Marceau; Rucker-Martin, Catherine; Dorfmüller, Peter; Lecerf, Florence; Vinhas, Maria C; Khatib, Salam; Haick, Hossam; Cohen-Kaminsky, Sylvia; Humbert, Marc; Montani, David; Perros, Frédéric.
Afiliación
  • Caliez J; School of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
  • Riou M; INSERM UMR_S 999 "Pulmonary Hypertension: Pathophysiology and Novel Therapies", Hôpital Marie Lannelongue, Le Plessis-Robinson, France.
  • Manaud G; Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
  • Nakhleh MK; School of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
  • Quatredeniers M; INSERM UMR_S 999 "Pulmonary Hypertension: Pathophysiology and Novel Therapies", Hôpital Marie Lannelongue, Le Plessis-Robinson, France.
  • Rucker-Martin C; Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
  • Dorfmüller P; Pneumologie, Hopitaux universitaires de Strasbourg, Strasbourg, France.
  • Lecerf F; School of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
  • Vinhas MC; INSERM UMR_S 999 "Pulmonary Hypertension: Pathophysiology and Novel Therapies", Hôpital Marie Lannelongue, Le Plessis-Robinson, France.
  • Khatib S; School of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
  • Haick H; INSERM UMR_S 999 "Pulmonary Hypertension: Pathophysiology and Novel Therapies", Hôpital Marie Lannelongue, Le Plessis-Robinson, France.
  • Cohen-Kaminsky S; School of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
  • Humbert M; INSERM UMR_S 999 "Pulmonary Hypertension: Pathophysiology and Novel Therapies", Hôpital Marie Lannelongue, Le Plessis-Robinson, France.
  • Montani D; School of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
  • Perros F; INSERM UMR_S 999 "Pulmonary Hypertension: Pathophysiology and Novel Therapies", Hôpital Marie Lannelongue, Le Plessis-Robinson, France.
Pulm Circ ; 10(4): 2045894020907884, 2020.
Article en En | MEDLINE | ID: mdl-33149891
Trichloroethylene exposure is a major risk factor for pulmonary veno-occlusive disease. We demonstrated that trichloroethylene alters the endothelial barrier integrity, at least in part, through vascular endothelial (VE)-Cadherin internalisation, and suggested that this mechanism may play a role in the development of pulmonary veno-occlusive disease.
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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Pulm Circ Año: 2020 Tipo del documento: Article País de afiliación: Francia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Pulm Circ Año: 2020 Tipo del documento: Article País de afiliación: Francia