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Monitoring of the Sensitivity In Vivo of Plasmodium falciparum to Artemether-Lumefantrine in Mali.
Diarra, Modibo; Coulibaly, Drissa; Tapily, Amadou; Guindo, Boureima; Sanogo, Koualy; Koné, Diakalia; Koné, Youssouf; Koné, Karim; Bathily, Aboudramane; Yattara, Oumar; Thera, Mahamadou A; Dicko, Alassane; Djimdé, Abdoulaye A; Sagara, Issaka.
Afiliación
  • Diarra M; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Coulibaly D; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Tapily A; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Guindo B; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Sanogo K; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Koné D; National Malaria Control Program (PNLP-Mali), Bamako 223, Mali.
  • Koné Y; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Koné K; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Bathily A; Populations Services International-Mali (PSI-Mali), Bamako E5397, Mali.
  • Yattara O; Populations Services International-Mali (PSI-Mali), Bamako E5397, Mali.
  • Thera MA; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Dicko A; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Djimdé AA; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
  • Sagara I; Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences Techniques and Technology of Bamako, Bamako BP 1805, Mali.
Trop Med Infect Dis ; 6(1)2021 Jan 24.
Article en En | MEDLINE | ID: mdl-33498803
In Mali, since 2007, artemether-lumefantrine has been the first choice against uncomplicated malaria. Despite its effectiveness, a rapid selection of markers of resistance to partner drugs has been documented. This work evaluated the treatment according to the World Health Organization's standard 28-day treatment method. The primary endpoint was the clinical and parasitological response corrected by a polymerase chain reaction. It was more than 99.9 percent, the proportion of patients with anemia significantly decrease compared to baseline (p < 0.001), and no serious events were recorded. Plasmodium falciparum remains sensitive to artemether-lumefantrine in Mali.
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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: Trop Med Infect Dis Año: 2021 Tipo del documento: Article País de afiliación: Mali

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: Trop Med Infect Dis Año: 2021 Tipo del documento: Article País de afiliación: Mali