Leveraging copper import by yersiniabactin siderophore system for targeted PET imaging of bacteria.

Siddiqui, Nabil A; Houson, Hailey A; Kamble, Nitin S; Blanco, Jose R; O'Donnell, Robert E; Hassett, Daniel J; Lapi, Suzanne E; Kotagiri, Nalinikanth

Siddiqui, Nabil A; Houson, Hailey A; Kamble, Nitin S; Blanco, Jose R; O'Donnell, Robert E; Hassett, Daniel J; Lapi, Suzanne E; Kotagiri, Nalinikanth.

Afiliación

Siddiqui NA; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, Ohio, USA.
Houson HA; Division of Advanced Medical Imaging Research, Department of Radiology and Chemistry, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Kamble NS; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, Ohio, USA.
Blanco JR; Division of Advanced Medical Imaging Research, Department of Radiology and Chemistry, University of Alabama at Birmingham, Birmingham, Alabama, USA.
O'Donnell RE; Department of Internal Medicine, Heart, Lung and Vascular Institute, and.
Hassett DJ; Department of Molecular Genetics, Biochemistry and Microbiology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Lapi SE; Division of Advanced Medical Imaging Research, Department of Radiology and Chemistry, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Kotagiri N; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, Ohio, USA.

JCI Insight ; 6(10)2021 05 24.

Article en En | MEDLINE | ID: mdl-34027898

Asunto(s)

Infecciones Bacterianas; Cobre/metabolismo; Fenoles; Tomografía de Emisión de Positrones/métodos; Sideróforos; Tiazoles; Animales; Bacterias/química; Bacterias/metabolismo; Infecciones Bacterianas/diagnóstico por imagen; Infecciones Bacterianas/microbiología; Modelos Animales de Enfermedad; Ecocardiografía; Femenino; Ratones; Ratones Endogámicos BALB C; Imagen Molecular; Fenoles/análisis; Fenoles/química; Fenoles/metabolismo; Sideróforos/análisis; Sideróforos/química; Sideróforos/metabolismo; Tiazoles/análisis; Tiazoles/química; Tiazoles/metabolismo

Palabras clave

Bacterial infections; Diagnostic imaging; Infectious disease

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fenoles / Tiazoles / Infecciones Bacterianas / Sideróforos / Cobre / Tomografía de Emisión de Positrones Límite: Animals Idioma: En Revista: JCI Insight Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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