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Guidelines for clinical trials of frontal fibrosing alopecia: consensus recommendations from the International FFA Cooperative Group (IFFACG).
Olsen, E A; Harries, M; Tosti, A; Bergfeld, W; Blume-Peytavi, U; Callender, V; Chasapi, V; Correia, O; Cotsarelis, G; Dhurat, R; Dlova, N; Doche, I; Enechukwu, N; Grimalt, R; Itami, S; Hordinsky, M; Khobzei, K; Lee, W-S; Malakar, S; Messenger, A; McMichael, A; Mirmirani, P; Ovcharenko, Y; Papanikou, S; Pinto, G M; Piraccini, B M; Pirmez, R; Reygagne, P; Roberts, J; Rudnicka, L; Saceda-Corralo, D; Shapiro, J; Silyuk, T; Sinclair, R; Soares, R O; Souissi, A; Vogt, A; Washenik, K; Zlotogorski, A; Canfield, D; Vano-Galvan, S.
Afiliación
  • Olsen EA; Duke University Medical Center, Durham, NC, USA.
  • Harries M; University of Manchester, MAHSC and NIHR Manchester Biomedical Research Centre, Salford Royal NHS Foundation Trust, Salford, UK.
  • Tosti A; University of Miami Miller School of Medicine, Miami, FL, USA.
  • Bergfeld W; Cleveland Clinic, Cleveland, OH, USA.
  • Blume-Peytavi U; Charité-Universitaetsmedizin, Berlin, Germany.
  • Callender V; Callender Dermatology & Cosmetic Center and Howard University College of Medicine, Washington, DC, USA.
  • Chasapi V; Andreas Sygros Hospital, Athens, Greece.
  • Correia O; Centro Dermatologia Epidermis, Porto, Portugal.
  • Cotsarelis G; University of Pennsylvania, Philadelphia, PA, USA.
  • Dhurat R; LTM Medical College & Hospital Sion, Mumbai, India.
  • Dlova N; University of KwaZulu Natal, Durban, South Africa.
  • Doche I; University of Sao Paulo Medical School, Sao Paulo, SP, Brazil.
  • Enechukwu N; Nnamdi Azikiwe University Awka, Anambra State, Nigeria.
  • Grimalt R; Universitat Internacional de Catalunya, Barcelona, Spain.
  • Itami S; Oita University, Oita, Japan.
  • Hordinsky M; University of Minnesota Medical School, Minneapolis, MN, USA.
  • Khobzei K; Kyiv Medical University, Kyiv, Ukraine.
  • Lee WS; Yonsei University, Wonju College of Medicine, Wonju, Gangwon-do, Republic of Korea.
  • Malakar S; Rita Skin Foundation, Kolkata, West Bengal, India.
  • Messenger A; Royal Hallamshire Hospital, Sheffield, UK.
  • McMichael A; Wake Forest School of Medicine, Winston Salem, NC, USA.
  • Mirmirani P; Kaiser Permanente Northern California, Vallejo, CA, USA.
  • Ovcharenko Y; V.N. Karazin Kharkiv National University, Kharkiv, Ukraine.
  • Papanikou S; Andreas Sygros Hospital, Athens, Greece.
  • Pinto GM; University of Miami Miller School of Medicine, Miami, FL, USA.
  • Piraccini BM; University of Bologna, Bologna, Italy.
  • Pirmez R; Instituto de Dermatologia Professor Rubem David Azulay - Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
  • Reygagne P; Centre Sabouraud, Hôpital Saint Louis, Paris, France.
  • Roberts J; Northwest Dermatology Institute, Portland, OR, USA.
  • Rudnicka L; Medical University of Warsaw, Warsaw, Poland.
  • Saceda-Corralo D; Ramón y Cajal Hospital, IRYCIS, University of Alcala, Madrid, Spain.
  • Shapiro J; New York University Grossman School of Medicine, New York, NY, USA.
  • Silyuk T; Hair Treatment and Transplantation Center Private Practice, Saint Petersburg, Russia.
  • Sinclair R; University of Melbourne and Sinclair Dermatology, Melbourne, VIC, Australia.
  • Soares RO; Cuf Descobertas Hospital, Lisbon, Portugal.
  • Souissi A; Department of Dermatology, University of Tunis El Manar, Tunis, Tunisia.
  • Vogt A; Charité-Universitaetsmedizin, Berlin, Germany.
  • Washenik K; Bosley Medical Group, Beverly Hills, CA and New York University Grossman School of Medicine, New York, NY, USA.
  • Zlotogorski A; Hadassah Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.
  • Canfield D; Canfield Scientific, Inc, Parsippany, NJ, USA.
  • Vano-Galvan S; Ramón y Cajal Hospital, IRYCIS, University of Alcala, Madrid, Spain.
Br J Dermatol ; 185(6): 1221-1231, 2021 12.
Article en En | MEDLINE | ID: mdl-34105768
ABSTRACT

BACKGROUND:

Frontal fibrosing alopecia (FFA) has become one of the most common causes of cicatricial alopecia worldwide. However, there is a lack of clear aetiology and robust clinical trial evidence for the efficacy and safety of agents currently used for treatment.

OBJECTIVES:

To enable data to be collected worldwide on FFA using common criteria and assessment methods.

METHODS:

A multicentre, international group of experts in hair loss was convened by email to create consensus recommendations for clinical trials. Consensus was defined at > 90% agreement on each recommended part of these guidelines.

RESULTS:

Standardized diagnostic criteria, severity rating, staging, and investigator and patient assessment of scalp hair loss and other clinical features of FFA were created.

CONCLUSIONS:

These guidelines should allow the collection of reliable aggregate data on FFA and advance efforts in both clinical and basic research to close knowledge gaps in this condition.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ensayos Clínicos como Asunto / Guías como Asunto / Alopecia / Liquen Plano Tipo de estudio: Etiology_studies / Guideline Límite: Humans Idioma: En Revista: Br J Dermatol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ensayos Clínicos como Asunto / Guías como Asunto / Alopecia / Liquen Plano Tipo de estudio: Etiology_studies / Guideline Límite: Humans Idioma: En Revista: Br J Dermatol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos