RNAi-mediated gene knockdown of progesterone 5ß-reductases in Digitalis lanata reduces 5ß-cardenolide content.

Klein, Jan; Horn, Elisa; Ernst, Mona; Leykauf, Tim; Leupold, Tamara; Dorfner, Maja; Wolf, Laura; Ignatova, Anastasiia; Kreis, Wolfgang; Munkert, Jennifer

Klein, Jan; Horn, Elisa; Ernst, Mona; Leykauf, Tim; Leupold, Tamara; Dorfner, Maja; Wolf, Laura; Ignatova, Anastasiia; Kreis, Wolfgang; Munkert, Jennifer.

Afiliación

Klein J; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
Horn E; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
Ernst M; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
Leykauf T; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
Leupold T; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
Dorfner M; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
Wolf L; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
Ignatova A; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
Kreis W; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
Munkert J; Department of Biology, University of Erlangen-Nuremberg, 91058, Erlangen, Germany. jennifer.munkert@fau.de.

Plant Cell Rep ; 40(9): 1631-1646, 2021 Sep.

Article en En | MEDLINE | ID: mdl-34146141

Asunto(s)

Cardenólidos/metabolismo; Digitalis/genética; Digitalis/metabolismo; Oxidorreductasas/genética; Proteínas de Plantas/genética; Butanonas/farmacología; Butionina Sulfoximina/farmacología; Digitalis/efectos de los fármacos; Regulación de la Expresión Génica de las Plantas; Técnicas de Silenciamiento del Gen; Glutatión/farmacología; Oxidorreductasas/metabolismo; Proteínas de Plantas/metabolismo; Brotes de la Planta/genética; Plantas Modificadas Genéticamente; Progesterona/farmacología; Interferencia de ARN; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo

Palabras clave

Cardenolide biosynthesis; Digitalis lanata; Glutathione; Progesterone 5ß-reductases (P5ßR); RNAi-mediated knockdown; Reactive electrophile species

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Proteínas de Plantas / Cardenólidos / Digitalis Idioma: En Revista: Plant Cell Rep Asunto de la revista: BOTANICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania

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