Exosomal long non-coding RNA SOX2 overlapping transcript enhances the resistance to EGFR-TKIs in non-small cell lung cancer cell line H1975.

Zhou, Dongbo; Xia, Zhi; Xie, Mingxuan; Gao, Ying; Yu, Qiao; He, Baimei

Zhou, Dongbo; Xia, Zhi; Xie, Mingxuan; Gao, Ying; Yu, Qiao; He, Baimei.

Afiliación

Zhou D; Department of Geriatric, Respiratory Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha, 410008, China.
Xia Z; Clinical Research Center for Geriatric Disorders National, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha, 410008, China.
Xie M; Xiangya Lung Cancer Center, Xiangya Hospital, Central South University, Changsha, China.
Gao Y; Department of Geriatric, Respiratory Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha, 410008, China.
Yu Q; Clinical Research Center for Geriatric Disorders National, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha, 410008, China.
He B; Department of Geriatric, Respiratory Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha, 410008, China.

Hum Cell ; 34(5): 1478-1489, 2021 Sep.

Article en En | MEDLINE | ID: mdl-34244990

Asunto(s)

Carcinoma de Pulmón de Células no Pequeñas/genética; Carcinoma de Pulmón de Células no Pequeñas/patología; Resistencia a Antineoplásicos/genética; Exosomas/genética; Regulación Neoplásica de la Expresión Génica/genética; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patología; Inhibidores de Proteínas Quinasas/farmacología; Proteínas Tirosina Quinasas/antagonistas & inhibidores; ARN Largo no Codificante/genética; Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico; Línea Celular Tumoral; Receptores ErbB/antagonistas & inhibidores; Humanos; Neoplasias Pulmonares/tratamiento farmacológico; Inhibidores de Proteínas Quinasas/uso terapéutico; ARN Largo no Codificante/fisiología

Palabras clave

Drug resistance; Epidermal growth factor receptor tyrosine kinase inhibitors; Macrophages; Non-small cell lung cancer; SOX2 overlapping transcript

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Tirosina Quinasas / Regulación Neoplásica de la Expresión Génica / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Inhibidores de Proteínas Quinasas / Exosomas / ARN Largo no Codificante / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Hum Cell Año: 2021 Tipo del documento: Article País de afiliación: China

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