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Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity.
Hutton, Colin; Heider, Felix; Blanco-Gomez, Adrian; Banyard, Antonia; Kononov, Alexander; Zhang, Xiaohong; Karim, Saadia; Paulus-Hock, Viola; Watt, Dale; Steele, Nina; Kemp, Samantha; Hogg, Elizabeth K J; Kelly, Joanna; Jackstadt, Rene-Filip; Lopes, Filipa; Menotti, Matteo; Chisholm, Luke; Lamarca, Angela; Valle, Juan; Sansom, Owen J; Springer, Caroline; Malliri, Angeliki; Marais, Richard; Pasca di Magliano, Marina; Zelenay, Santiago; Morton, Jennifer P; Jørgensen, Claus.
Afiliación
  • Hutton C; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Heider F; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Blanco-Gomez A; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Banyard A; Flow Cytometry Core, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Kononov A; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Zhang X; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Karim S; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK.
  • Paulus-Hock V; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK.
  • Watt D; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK.
  • Steele N; University of Michigan, Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA; Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, Ann Arbor, MI 48109, USA.
  • Kemp S; Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA; Molecular and Cellular Pathology Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA.
  • Hogg EKJ; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Kelly J; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Jackstadt RF; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK.
  • Lopes F; Drug Discovery Unit, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Menotti M; Cell Signalling, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Chisholm L; Molecular Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Lamarca A; Department of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
  • Valle J; Department of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK; Institute of Cancer Sciences, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.
  • Sansom OJ; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Switchback Road, Garscube Estate, Glasgow G61 1QH, UK.
  • Springer C; Drug Discovery Unit, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Malliri A; Cell Signalling, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Marais R; Molecular Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Pasca di Magliano M; University of Michigan, Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA; Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
  • Zelenay S; Cancer Immunity and Inflammation, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK.
  • Morton JP; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Switchback Road, Garscube Estate, Glasgow G61 1QH, UK.
  • Jørgensen C; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK. Electronic address: claus.jorgensen@cruk.manchester.ac.uk.
Cancer Cell ; 39(9): 1227-1244.e20, 2021 09 13.
Article en En | MEDLINE | ID: mdl-34297917
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Análisis de la Célula Individual / Fibroblastos Asociados al Cáncer / Endoglina Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Análisis de la Célula Individual / Fibroblastos Asociados al Cáncer / Endoglina Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido