[Impact of overweight and obesity on the relationship between serum vitamin D and fasting blood glucose in children aged 6-17 years in Shandong Province].

ABSTRACT

OBJECTIVE: To study the relationship between serum vitamin D and fasting blood glucose in children and adolescents, and its influence on overweight and obesity. METHODS: Using a multi-stage stratified cluster sampling method, 13 districts and counties in Shandong Province were selected as survey points, and a total of 26 elementary schools, 26 junior high schools and 13 high schools were selected. Questionnaire surveys and physical examination were conducted on children and adolescents aged 6-17.Serum vitamin D and fasting blood glucose were uniformly measured. The "BMI Classification Standard for Overweight and Obesity Screening for Chinese School-age Children and Adolescents" was used to determine overweight and obesity. Statistical method adopt t-test and generalized linear regression model for analysis. RESULTS: A total of 3562 children aged 6-17 years were investigated, 2666 were healthy, 446 were overweight, 450 were obese, including 131 peripheral obesity and 319 abdominal obesity. The fasting blood glucose level of the 13-17-year-old group was significantly higher than that of the 6-12-year-old group(t=-3.13, P=0.002), and the male was significantly higher than that of the female(t=7.87, P& lt; 0.001). In the healthy and obesity group, there was a negative correlation between serum vitamin D and fasting blood glucose(P& lt; 0.05). In overweight group, serum vitamin D was not significantly related to fasting blood glucose(P& gt; 0.05). Serum vitamin D and fasting blood glucose were negatively correlated with healthy bodies in female group and 13-17 years old group, and the abdominal obesity bodies in the 6-12 year old group(P& lt; 0.05). CONCLUSION: The fasting blood glucose of adolescents aged 13-17 is significantly higher than that of children aged 6-12, and the fasting blood glucose of men is significantly higher than that of women. Different gender, age, and overweight and obesity status have an impact on the relationship between serum vitamin D and fasting blood glucose.