An early proinflammatory transcriptional response to tau pathology is age-specific and foreshadows reduced tau burden.

Rasmussen, Jay; Ewing, Adam D; Bodea, Liviu-Gabriel; Bodea, Gabriela O; Gearing, Marla; Faulkner, Geoffrey J

Rasmussen, Jay; Ewing, Adam D; Bodea, Liviu-Gabriel; Bodea, Gabriela O; Gearing, Marla; Faulkner, Geoffrey J.

Afiliación

Rasmussen J; Queensland Brain Institute, University of Queensland, St Lucia, Brisbane, Queensland, Australia.
Ewing AD; Mater Research Institute, University of Queensland, Woolloongabba, Queensland, Australia.
Bodea LG; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, University of Queensland, St Lucia, Brisbane, Queensland, Australia.
Bodea GO; Queensland Brain Institute, University of Queensland, St Lucia, Brisbane, Queensland, Australia.
Gearing M; Mater Research Institute, University of Queensland, Woolloongabba, Queensland, Australia.
Faulkner GJ; Departments of Pathology and Laboratory Medicine and Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.

Brain Pathol ; 32(3): e13018, 2022 05.

Article en En | MEDLINE | ID: mdl-34463402

Asunto(s)

Enfermedad de Alzheimer; Proteínas tau; Factores de Edad; Enfermedad de Alzheimer/patología; Animales; Modelos Animales de Enfermedad; Ratones; Ratones Transgénicos; Microglía/patología; Agregado de Proteínas; Proteínas tau/genética; Proteínas tau/metabolismo

Palabras clave

RNA-seq; aging; tauopathy

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas tau / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Brain Pathol Asunto de la revista: CEREBRO / PATOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Australia

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