Neuroprotective effect of sumatriptan in pentylenetetrazole-induced seizure is mediated through N-methyl-D-aspartate/nitric oxide and cAMP response element-binding protein signaling pathway.

Mumtaz, Faiza; Rashki, Asma; Imran Khan, Muhammad; Shadboorestan, Amir; Abdollahi, Alireza; Ghazi-Khansari, Mahmoud; Alotaibi, Ghallab; Dehpour, Ahmad Reza

Mumtaz, Faiza; Rashki, Asma; Imran Khan, Muhammad; Shadboorestan, Amir; Abdollahi, Alireza; Ghazi-Khansari, Mahmoud; Alotaibi, Ghallab; Dehpour, Ahmad Reza.

Afiliación

Mumtaz F; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Rashki A; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Imran Khan M; International Campus of Tehran University of Medical Sciences, Tehran, Iran.
Shadboorestan A; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Abdollahi A; Department of Pharmacology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Ghazi-Khansari M; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Alotaibi G; Department of Toxicology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Dehpour AR; Department of Pathology, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Fundam Clin Pharmacol ; 36(2): 250-261, 2022 Apr.

Article en En | MEDLINE | ID: mdl-34545607

Asunto(s)

Proteína de Unión a Elemento de Respuesta al AMP Cíclico; Fármacos Neuroprotectores; Convulsiones; Sumatriptán; Animales; Proteína de Unión a Elemento de Respuesta al AMP Cíclico/metabolismo; Ratones; N-Metilaspartato/farmacología; Fármacos Neuroprotectores/farmacología; Fármacos Neuroprotectores/uso terapéutico; Óxido Nítrico/metabolismo; Pentilenotetrazol/farmacología; Convulsiones/inducido químicamente; Convulsiones/tratamiento farmacológico; Convulsiones/prevención & control; Transducción de Señal; Sumatriptán/farmacología; Sumatriptán/uso terapéutico

Palabras clave

N-methyl-D-aspartate; cAMP response element-binding protein; mice; nitric oxide; pentylenetetrazole; seizure; sumatriptan

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Convulsiones / Proteína de Unión a Elemento de Respuesta al AMP Cíclico / Sumatriptán / Fármacos Neuroprotectores Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Fundam Clin Pharmacol Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Irán

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