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ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine.
Rahmani, Nora E; Ramachandra, Nandini; Sahu, Srabani; Gitego, Nadege; Lopez, Andrea; Pradhan, Kith; Bhagat, Tushar D; Gordon-Mitchell, Shanisha; Pena, Bianca Rivera; Kazemi, Mohammad; Rao, Keshav; Giricz, Orsi; Maqbool, Shahina Bano; Olea, Raul; Zhao, Yongmei; Zhang, Jinghang; Dolatshad, Hamid; Tittrea, Vickram; Tatwavedi, Dharamveer; Singh, Shalini; Lee, Juseong; Sun, Tianyu; Steidl, Ulrich; Shastri, Aditi; Inoue, Daichi; Abdel-Wahab, Omar; Pellagatti, Andrea; Gavathiotis, Evripidis; Boultwood, Jacqueline; Verma, Amit.
Afiliación
  • Rahmani NE; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Ramachandra N; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Sahu S; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Gitego N; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Lopez A; Department of Biochemistry, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Pradhan K; Department of Biochemistry, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Bhagat TD; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Gordon-Mitchell S; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Pena BR; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Kazemi M; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Rao K; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Giricz O; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Maqbool SB; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Olea R; Department of Genetics, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Zhao Y; Department of Genetics, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Zhang J; Department of Genetics, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Dolatshad H; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Tittrea V; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Tatwavedi D; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Singh S; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Lee J; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Sun T; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Steidl U; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Shastri A; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Inoue D; Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Abdel-Wahab O; Department of Medicine, Division of Hemato-Oncology, Montefiore Medical Center, Albert Einstein Cancer Center, Bronx, NY, USA.
  • Pellagatti A; Department of Developmental and Molecular Biology, Montefiore Medical Center, Albert Einstein Cancer Center, Bronx, NY, USA.
  • Gavathiotis E; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Boultwood J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Verma A; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Blood Cancer J ; 11(9): 157, 2021 09 21.
Article en En | MEDLINE | ID: mdl-34548471
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Sulfonamidas / Azacitidina / Leucemia Mielógena Crónica BCR-ABL Positiva / Compuestos Bicíclicos Heterocíclicos con Puentes / Antineoplásicos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Blood Cancer J Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Sulfonamidas / Azacitidina / Leucemia Mielógena Crónica BCR-ABL Positiva / Compuestos Bicíclicos Heterocíclicos con Puentes / Antineoplásicos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Blood Cancer J Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos