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The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model.
Abdelnabi, Rana; Foo, Caroline S; Kaptein, Suzanne J F; Zhang, Xin; Do, Thuc Nguyen Dan; Langendries, Lana; Vangeel, Laura; Breuer, Judith; Pang, Juanita; Williams, Rachel; Vergote, Valentijn; Heylen, Elisabeth; Leyssen, Pieter; Dallmeier, Kai; Coelmont, Lotte; Chatterjee, Arnab K; Mols, Raf; Augustijns, Patrick; De Jonghe, Steven; Jochmans, Dirk; Weynand, Birgit; Neyts, Johan.
Afiliación
  • Abdelnabi R; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Foo CS; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Kaptein SJF; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Zhang X; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Do TND; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Langendries L; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Vangeel L; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Breuer J; UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, United Kingdom.
  • Pang J; UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, United Kingdom.
  • Williams R; UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, United Kingdom.
  • Vergote V; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Heylen E; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Leyssen P; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Dallmeier K; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Coelmont L; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Chatterjee AK; Calibr at Scripps Research, La Jolla, CA 92037, USA.
  • Mols R; KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Drug Delivery & Disposition, Box 921, 3000 Leuven, Belgium.
  • Augustijns P; KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Drug Delivery & Disposition, Box 921, 3000 Leuven, Belgium.
  • De Jonghe S; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Jochmans D; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
  • Weynand B; KU Leuven Department of Imaging and Pathology, Translational Cell and Tissue Research, Division of Translational Cell and Tissue Research, B-3000 Leuven, Belgium.
  • Neyts J; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium; Global Virus Network, GVN, Baltimore, MD 21201, USA.
EBioMedicine ; 72: 103595, 2021 Oct.
Article en En | MEDLINE | ID: mdl-34571361
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Citidina / Amidas / Tratamiento Farmacológico de COVID-19 / Hidroxilaminas / Pulmón Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: EBioMedicine Año: 2021 Tipo del documento: Article País de afiliación: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Citidina / Amidas / Tratamiento Farmacológico de COVID-19 / Hidroxilaminas / Pulmón Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: EBioMedicine Año: 2021 Tipo del documento: Article País de afiliación: Bélgica