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Machine Learning Models for Human In Vivo Pharmacokinetic Parameters with In-House Validation.
Miljkovic, Filip; Martinsson, Anton; Obrezanova, Olga; Williamson, Beth; Johnson, Martin; Sykes, Andy; Bender, Andreas; Greene, Nigel.
Afiliación
  • Miljkovic F; Data Science and AI, Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Gothenburg SE-43183, Sweden.
  • Martinsson A; Data Science and AI, Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Gothenburg SE-43183, Sweden.
  • Obrezanova O; Data Science and AI, Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge CB4 0FZ, U.K.
  • Williamson B; Drug Metabolism and Pharmacokinetics, Research and Early Development, Oncology, R&D, AstraZeneca, Cambridge CB10 1XL, U.K.
  • Johnson M; Clinical Pharmacology & Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge SG8 6HB, U.K.
  • Sykes A; Clinical Pharmacology & Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge SG8 6HB, U.K.
  • Bender A; Data Science and AI, Imaging and Data Analytics, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge CB4 0FZ, U.K.
  • Greene N; Department of Chemistry, Centre for Molecular Informatics, University of Cambridge, Cambridge CB2 1EW, U.K.
Mol Pharm ; 18(12): 4520-4530, 2021 12 06.
Article en En | MEDLINE | ID: mdl-34758626
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Farmacocinética / Aprendizaje Automático Tipo de estudio: Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Suecia
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Farmacocinética / Aprendizaje Automático Tipo de estudio: Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Suecia