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Hit-and-run: a Swedish nationwide cohort study of serious transport accidents and convictions due to traffic offenses in obsessive-compulsive disorder.
Mataix-Cols, David; Fernández de la Cruz, Lorena; Brander, Gustaf; Andersson, Erik; D'Onofrio, Brian M; Rück, Christian; Larsson, Henrik; Lichtenstein, Paul; Sidorchuk, Anna.
Afiliación
  • Mataix-Cols D; Department of Clinical Neuroscience, Child and Adolescent Psychiatry Research Centre, Karolinska Institutet, Gävlegatan 22B, 8th floor, 113 30 , Stockholm, Sweden. david.mataix.cols@ki.se.
  • Fernández de la Cruz L; Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden. david.mataix.cols@ki.se.
  • Brander G; Department of Clinical Neuroscience, Child and Adolescent Psychiatry Research Centre, Karolinska Institutet, Gävlegatan 22B, 8th floor, 113 30 , Stockholm, Sweden.
  • Andersson E; Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
  • D'Onofrio BM; Department of Clinical Neuroscience, Child and Adolescent Psychiatry Research Centre, Karolinska Institutet, Gävlegatan 22B, 8th floor, 113 30 , Stockholm, Sweden.
  • Rück C; Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
  • Larsson H; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Lichtenstein P; Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Sidorchuk A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Soc Psychiatry Psychiatr Epidemiol ; 57(9): 1817-1827, 2022 Sep.
Article en En | MEDLINE | ID: mdl-34779877
ABSTRACT

PURPOSE:

Individuals with obsessive-compulsive disorder (OCD) often report driving-related obsessions, such as fears of causing accidents, but the risk of transport accidents in OCD is unknown. We investigated whether individuals with OCD have an increased risk of serious transport accidents and convictions due to traffic offenses and explored the role of psychiatric comorbidities.

METHODS:

We included all individuals ≥ 18 years living in Sweden between 1997 and 2013 (N = 5,760,734). A total of 23,126 individuals had a diagnosis of OCD in the National Patient Register. We also identified 16,607 families with full siblings discordant for OCD. Cox proportional hazards regression models estimated hazard ratios (HRs) with 95% confidence intervals (CIs) for the risk of three outcomes in individuals with OCD, compared to unexposed individuals and their unexposed full siblings injuries or deaths due to transport accidents, injuries or deaths due to motor vehicle accidents, and convictions related to traffic offenses. Psychiatric comorbidities were systematically adjusted for.

RESULTS:

Women, but not men, with OCD had a marginally increased risk of serious transport accidents (adjusted HR = 1.20 [95% CI 1.13-1.28]) and motor vehicle accidents (adjusted HR = 1.20 [95% CI 1.09-1.31]), compared to unaffected individuals. Neither women nor men with OCD had a significantly increased risk of convictions. The sibling comparisons showed no significant associations. When psychiatric comorbidities were adjusted for, several observed associations became non-significant or inversed (HRs and 95% CIs below one).

CONCLUSION:

The risks of serious transport accidents and driving-related criminal convictions in OCD are negligible and heavily influenced by psychiatric comorbidity.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trastorno Obsesivo Compulsivo Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans País/Región como asunto: Europa Idioma: En Revista: Soc Psychiatry Psychiatr Epidemiol Asunto de la revista: CIENCIAS SOCIAIS / EPIDEMIOLOGIA / PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Suecia

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trastorno Obsesivo Compulsivo Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans País/Región como asunto: Europa Idioma: En Revista: Soc Psychiatry Psychiatr Epidemiol Asunto de la revista: CIENCIAS SOCIAIS / EPIDEMIOLOGIA / PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Suecia