Results of concurrent radiotherapy and immunotherapy in recurrent and metastatic head and neck cancer: A single-center experience.
Oral Oncol
; 124: 105658, 2022 01.
Article
en En
| MEDLINE
| ID: mdl-34883400
ABSTRACT
OBJECTIVES:
In metastatic and recurrent head and neck cancer (M/R HN-SCC), the median survival is less than a year and locoregional recurrence is the main cause of death. Our aim was to evaluate the results of concurrent stereotactic body radiotherapy (SBRT) and immunotherapy (ICI) in these patients. MATERIALS ANDMETHODS:
Fifteen patients diagnosed with M/R HN-SCC were evaluated retrospectively. All patients received SBRT (3x8 Gy) to all recurrent and metastatic foci with concurrent ICI.RESULTS:
Six months overall survival (OS) rates and progression-free survival (PFS) rates were 93% and 86%, respectively. Local control (LC) rate in the site of SBRT was 96%. Higher survival and LC rates were achieved with lower doses of radiotherapy with the synergistic effect of SBRT and ICI.CONCLUSION:
Concurrent ICI and SBRT was feasible with excellent LC.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Radiocirugia
/
Neoplasias de Cabeza y Cuello
Tipo de estudio:
Observational_studies
Límite:
Humans
Idioma:
En
Revista:
Oral Oncol
Asunto de la revista:
NEOPLASIAS
Año:
2022
Tipo del documento:
Article