Antinociceptive activities of a novel diarylpentanoid analogue, 2-benzoyl-6-(3-bromo-4-hydroxybenzylidene)cyclohexen-1-ol, and its possible mechanisms of action in mice.

Ong, Hui Ming; Azmi, Ahmad Farhan Ahmad; Leong, Sze Wei; Abas, Faridah; Perimal, Enoch Kumar; Farouk, Ahmad Akira Omar; Israf, Daud Ahmad; Sulaiman, Mohd Roslan

Ong, Hui Ming; Azmi, Ahmad Farhan Ahmad; Leong, Sze Wei; Abas, Faridah; Perimal, Enoch Kumar; Farouk, Ahmad Akira Omar; Israf, Daud Ahmad; Sulaiman, Mohd Roslan.

Afiliación

Ong HM; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Azmi AFA; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Leong SW; UPM-MAKNA Cancer Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Abas F; Department of Food Sciences, Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Perimal EK; Natural Medicines and Product Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Farouk AAO; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Israf DA; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Sulaiman MR; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.

Sci Rep ; 11(1): 24121, 2021 12 16.

Article en En | MEDLINE | ID: mdl-34916536

Asunto(s)

Analgésicos; Dolor/tratamiento farmacológico; Analgésicos/farmacología; Analgésicos/uso terapéutico; Animales; Compuestos de Bencilo/farmacología; Compuestos de Bencilo/uso terapéutico; Compuestos de Bromina/farmacología; Compuestos de Bromina/uso terapéutico; Modelos Animales de Enfermedad; Evaluación Preclínica de Medicamentos/métodos; Glutamatos; Masculino; Ratones; Ratones Endogámicos ICR; Neurotransmisores; Óxido Nítrico/antagonistas & inhibidores; Células RAW 264.7; Receptores Opioides; Canales Catiónicos TRPV

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Dolor / Analgésicos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Malasia

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