Vitamin E enriched diet increases the rate of orthodontic tooth movement.
Am J Orthod Dentofacial Orthop
; 161(5): 687-697.e3, 2022 May.
Article
en En
| MEDLINE
| ID: mdl-35012806
ABSTRACT
INTRODUCTION:
Vitamin E is a popular antioxidant suggested to affect bone turnover. However, the effects of a vitamin E enriched diet on the rate of tooth movement are unknown. Therefore, this study aimed to evaluate tooth movement in rats receiving a vitamin E enriched diet. In addition, we examined bone remodeling in experimental and control rats.METHODS:
Thirty-two 6-week-old male rats were divided into 4 groups (1) group 1 (n = 8) orthodontic tooth movement (OTM) for 4 days + regular diet; (2) group 2 (n = 8) OTM for 14 days + regular diet; (3) group 3 (n = 8) OTM for 4 days + vitamin E diet; and (4) group 4 (n = 8) - OTM for 14 days + vitamin E diet. Maxillary alveolar bones and femurs of rats were analyzed by microcomputed tomography and histology.RESULTS:
Rats fed a vitamin E diet presented an increased OTM rate at days 4 and 14. We found an increased number of osteoclasts and decreased bone volume in the vitamin E diet group at day 14 of OTM. In addition, there was increased expression of the microphthalmia-associated transcription factor in the alveolar bone of the vitamin E diet group. In contrast, there was no difference in bone remodeling in femurs or alveolar bone at the control side.CONCLUSIONS:
We found that an enriched vitamin E diet increases the rate of OTM in rats, suggesting that vitamin E may be useful as an avenue to accelerate OTM.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Técnicas de Movimiento Dental
/
Vitamina E
Límite:
Animals
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Humans
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Male
Idioma:
En
Revista:
Am J Orthod Dentofacial Orthop
Asunto de la revista:
ODONTOLOGIA
/
ORTODONTIA
Año:
2022
Tipo del documento:
Article