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Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation.
Kissel, Theresa; Ge, Changrong; Hafkenscheid, Lise; Kwekkeboom, Joanneke C; Slot, Linda M; Cavallari, Marco; He, Yibo; van Schie, Karin A; Vergroesen, Rochelle D; Kampstra, Arieke S B; Reijm, Sanne; Stoeken-Rijsbergen, Gerrie; Koeleman, Carolien; Voortman, Lennard M; Heitman, Laura H; Xu, Bingze; Pruijn, Ger J M; Wuhrer, Manfred; Rispens, Theo; Huizinga, Tom W J; Scherer, Hans Ulrich; Reth, Michael; Holmdahl, Rikard; Toes, Rene E M.
Afiliación
  • Kissel T; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Ge C; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden.
  • Hafkenscheid L; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Kwekkeboom JC; Department of Biotechnology and Biomedicine, DTU Bioengineering, Technical University of Denmark, Lyngby, Denmark.
  • Slot LM; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Cavallari M; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • He Y; Biology III (Department of Molecular Immunology), University of Freiburg, Freiburg, Germany.
  • van Schie KA; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden.
  • Vergroesen RD; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Kampstra ASB; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Reijm S; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Stoeken-Rijsbergen G; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Koeleman C; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Voortman LM; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.
  • Heitman LH; Department of Cell and Chemical Immunology, Leiden University Medical Center, Leiden, Netherlands.
  • Xu B; Oncode Institute and Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands.
  • Pruijn GJM; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden.
  • Wuhrer M; Department of Biomolecular Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, Netherlands.
  • Rispens T; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.
  • Huizinga TWJ; Department Immunopathology, Sanquin Research, Amsterdam, Netherlands.
  • Scherer HU; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Reth M; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
  • Holmdahl R; Biology III (Department of Molecular Immunology), University of Freiburg, Freiburg, Germany.
  • Toes REM; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden.
Sci Adv ; 8(6): eabm1759, 2022 Feb 11.
Article en En | MEDLINE | ID: mdl-35138894
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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Sci Adv Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Sci Adv Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos