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Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9.
Kwon, Taejoon; Ra, Jae Sun; Lee, Soyoung; Baek, In-Joon; Khim, Keon Woo; Lee, Eun A; Song, Eun Kyung; Otarbayev, Daniyar; Jung, Woojae; Park, Yong Hwan; Wie, Minwoo; Bae, Juyoung; Cheng, Himchan; Park, Jun Hong; Kim, Namwoo; Seo, Yuri; Yun, Seongmin; Kim, Ha Eun; Moon, Hyo Eun; Paek, Sun Ha; Park, Tae Joo; Park, Young Un; Rhee, Hwanseok; Choi, Jang Hyun; Cho, Seung Woo; Myung, Kyungjae.
Afiliación
  • Kwon T; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea; tkwon@unist.ac.kr swcho@unist.ac.kr kmyung@ibs.re.kr.
  • Ra JS; Department of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Lee S; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Baek IJ; Department of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Khim KW; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Lee EA; Cascure Therapeutics, Ulsan 44919, Republic of Korea.
  • Song EK; Department of Biological Sciences, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Otarbayev D; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Jung W; Department of Biological Sciences, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Park YH; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Wie M; Department of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Bae J; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Cheng H; Department of Biological Sciences, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Park JH; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Kim N; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Seo Y; Department of Biological Sciences, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Yun S; Department of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Kim HE; Department of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Moon HE; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Paek SH; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Park TJ; Department of Biological Sciences, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Park YU; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  • Rhee H; Department of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Choi JH; Department of Biological Sciences, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  • Cho SW; Department of Neurosurgery, Seoul National University Hospital, Seoul 03080, Republic of Korea.
  • Myung K; Department of Neurosurgery, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Proc Natl Acad Sci U S A ; 119(9)2022 03 01.
Article en En | MEDLINE | ID: mdl-35217600
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mutación INDEL / Sistemas CRISPR-Cas / Neoplasias Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mutación INDEL / Sistemas CRISPR-Cas / Neoplasias Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article