A Good Day for Helminths: how parasite-derived GDH suppresses inflammatory responses.
EMBO Rep
; 23(5): e55054, 2022 05 04.
Article
en En
| MEDLINE
| ID: mdl-35357756
ABSTRACT
Parasitic helminths are often associated with immunoregulation, which allows them to survive in their hosts in the face of type 2 immune responses. They achieve this feat through the secretion of multiple immunomodulatory factors. In this issue of EMBO Reports, Prodjinotho et al show that the parasitic cestode Taenia solium induces regulatory T-cell responses in mice and humans through the release of the metabolic enzyme Glutamate dehydrogenase (GDH), which may be a conserved pathway of immunoregulation in many helminths (Prodjinotho et al, 2022).
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Parásitos
/
Taenia solium
/
Helmintos
Límite:
Animals
Idioma:
En
Revista:
EMBO Rep
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2022
Tipo del documento:
Article
País de afiliación:
Reino Unido