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CRISPR-Cas9 treatment partially restores amyloid-ß 42/40 in human fibroblasts with the Alzheimer's disease PSEN 1 M146L mutation.
Konstantinidis, Evangelos; Molisak, Agnieszka; Perrin, Florian; Streubel-Gallasch, Linn; Fayad, Sarah; Kim, Daniel Y; Petri, Karl; Aryee, Martin J; Aguilar, Ximena; György, Bence; Giedraitis, Vilmantas; Joung, J Keith; Pattanayak, Vikram; Essand, Magnus; Erlandsson, Anna; Berezovska, Oksana; Ingelsson, Martin.
Afiliación
  • Konstantinidis E; Department of Public Health and Caring Sciences, Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Molisak A; Department of Public Health and Caring Sciences, Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Perrin F; Department of Neurology, Massachusetts General Hospital, Memory Disorders Unit, Harvard Medical School, Charlestown, MA, USA.
  • Streubel-Gallasch L; Department of Public Health and Caring Sciences, Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Fayad S; Department of Public Health and Caring Sciences, Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Kim DY; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.
  • Petri K; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.
  • Aryee MJ; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.
  • Aguilar X; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.
  • György B; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.
  • Giedraitis V; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.
  • Joung JK; Department of Pathology, Harvard Medical School, Boston, MA, USA.
  • Pattanayak V; Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA.
  • Essand M; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.
  • Erlandsson A; Department of Pathology, Harvard Medical School, Boston, MA, USA.
  • Berezovska O; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Ingelsson M; Department of Public Health and Caring Sciences, Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
Mol Ther Nucleic Acids ; 28: 450-461, 2022 Jun 14.
Article en En | MEDLINE | ID: mdl-35505961
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Año: 2022 Tipo del documento: Article País de afiliación: Suecia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Año: 2022 Tipo del documento: Article País de afiliación: Suecia