Targeting protein-protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model.

Dahal, Achyut; Parajuli, Pravin; Singh, Sitanshu S; Shrestha, Leeza; Sonju, Jafrin Jobayer; Shrestha, Prajesh; Chatzistamou, Ioulia; Jois, Seetharama

Dahal, Achyut; Parajuli, Pravin; Singh, Sitanshu S; Shrestha, Leeza; Sonju, Jafrin Jobayer; Shrestha, Prajesh; Chatzistamou, Ioulia; Jois, Seetharama.

Afiliación

Dahal A; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe LA, 71201, USA.
Parajuli P; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe LA, 71201, USA.
Singh SS; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe LA, 71201, USA.
Shrestha L; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe LA, 71201, USA.
Sonju JJ; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe LA, 71201, USA.
Shrestha P; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe LA, 71201, USA.
Chatzistamou I; Department of Pathology, Microbiology & Immunology (PMI), School of Medicine, USC, SC 6439 Garners Ferry Rd, Columbia, SC, 29208, USA.
Jois S; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe LA, 71201, USA. Electronic address: jois@ulm.edu.

J Pharmacol Sci ; 149(3): 124-138, 2022 Jul.

Article en En | MEDLINE | ID: mdl-35641025

Asunto(s)

Artritis Experimental; Artritis Reumatoide; Helianthus; Peptidomiméticos; Animales; Artritis Experimental/tratamiento farmacológico; Artritis Reumatoide/tratamiento farmacológico; Antígenos CD58/química; Antígenos CD58/metabolismo; Helianthus/química; Helianthus/metabolismo; Humanos; Inmunidad; Inmunomodulación; Ratones; Péptidos/farmacología; Péptidos Cíclicos/metabolismo; Péptidos Cíclicos/farmacología; Peptidomiméticos/farmacología; Peptidomiméticos/uso terapéutico; Inhibidores de Tripsina/uso terapéutico

Palabras clave

CD2; CD58; Grafted peptide; Proteinprotein interaction; Rheumatoid arthritis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Artritis Experimental / Artritis Reumatoide / Peptidomiméticos / Helianthus Límite: Animals / Humans Idioma: En Revista: J Pharmacol Sci Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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