Exercise, inflammation and acute cardiovascular events.
Exerc Immunol Rev
; 28: 93-103, 2022.
Article
en En
| MEDLINE
| ID: mdl-35671219
ABSTRACT
Individuals who participate in regular exercise over time have a markedly reduced risk of cardiovascular disease. Paradoxically, in susceptible individuals with underlying, often undiagnosed, disease states, exercise may acutely increase an individual's risk of cardiovascular events during and immediately following physical exertion. Exercise is thought to evoke conditions that trigger atheromatous plaque rupture or trigger life threatening arrhythmias in individuals with pre-existing, vulnerable coronary artery and inherited cardiovascular disease respectively. This transient increased risk may be driven by the inflammatory trigger provided by physical exertion where exercise is associated with an upregulation of inflammatory mediators in the acute phase. Conversely, habitual exercise can lead to a modulation of the inflammatory response over time. This review explores exercise related inflammation; acute cardiovascular events related to exercise and strategies to mitigate these risks.
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Banco de datos:
MEDLINE
Asunto principal:
Enfermedades Cardiovasculares
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Exerc Immunol Rev
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Reino Unido