Effective therapy of polymyositis in mice via selective inhibition of the immunoproteasome.

Del Rio Oliva, Marta; Kirk, Christopher J; Groettrup, Marcus; Basler, Michael

Del Rio Oliva, Marta; Kirk, Christopher J; Groettrup, Marcus; Basler, Michael.

Afiliación

Del Rio Oliva M; Division of Immunology, Department of Biology, University of Konstanz, Konstanz, Germany.
Kirk CJ; Kezar Life Sciences, South San Francisco, California, USA.
Groettrup M; Division of Immunology, Department of Biology, University of Konstanz, Konstanz, Germany.
Basler M; Biotechnology Institute Thurgau, University of Konstanz, Kreuzlingen, Switzerland.

Eur J Immunol ; 52(9): 1510-1522, 2022 09.

Article en En | MEDLINE | ID: mdl-35733374

Asunto(s)

Debilidad Muscular; Polimiositis; Animales; Creatina Quinasa/uso terapéutico; Humanos; Ratones; Morfolinas; Debilidad Muscular/tratamiento farmacológico; Polimiositis/tratamiento farmacológico; Polimiositis/patología; Complejo de la Endopetidasa Proteasomal

Palabras clave

C protein-induced myositis; KZR-616; ONX 0914; immunoproteasome inhibition; polymyositis; proteasome

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polimiositis / Debilidad Muscular Límite: Animals / Humans Idioma: En Revista: Eur J Immunol Año: 2022 Tipo del documento: Article País de afiliación: Alemania

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