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An antagonistic monoclonal anti-Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis.
Vogler, Melanie; Oleksy, Arkadiusz; Schulze, Sabrina; Fedorova, Marina; Kojonazarov, Baktybek; Nijjar, Sharandip; Patel, Seema; Jossi, Sian; Sawmynaden, Kovilen; Henry, Maud; Brown, Richard; Matthews, David; Offermanns, Stefan; Worzfeld, Thomas.
Afiliación
  • Vogler M; Department of Pharmacology, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany; LOEWE Center for Translational Medicine and Pharmacology, Frankfurt, Germany.
  • Oleksy A; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
  • Schulze S; Department of Pharmacology, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany; LOEWE Center for Translational Medicine and Pharmacology, Frankfurt, Germany.
  • Fedorova M; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
  • Kojonazarov B; Institute for Lung Health (ILH), University Hospital Giessen and Marburg, Medical Clinic II, Giessen, Germany.
  • Nijjar S; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
  • Patel S; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
  • Jossi S; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
  • Sawmynaden K; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
  • Henry M; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
  • Brown R; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
  • Matthews D; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
  • Offermanns S; Department of Pharmacology, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany; LOEWE Center for Translational Medicine and Pharmacology, Frankfurt, Germany; Faculty of Medicine, University of Frankfurt, Frankfurt, Germany.
  • Worzfeld T; Department of Pharmacology, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany; LOEWE Center for Translational Medicine and Pharmacology, Frankfurt, Germany; Institute of Pharmacology, University of Marburg, Marburg, Germany. Electronic address: worzfeld@uni-marburg.de.
J Biol Chem ; 298(9): 102265, 2022 09.
Article en En | MEDLINE | ID: mdl-35850304
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antígenos CD / Osteoporosis Posmenopáusica / Receptores de Superficie Celular / Semaforinas / Anticuerpos Monoclonales / Esclerosis Múltiple / Proteínas del Tejido Nervioso Límite: Animals / Female / Humans Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antígenos CD / Osteoporosis Posmenopáusica / Receptores de Superficie Celular / Semaforinas / Anticuerpos Monoclonales / Esclerosis Múltiple / Proteínas del Tejido Nervioso Límite: Animals / Female / Humans Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article País de afiliación: Alemania