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Extraction of Bioactive Compounds for Antioxidant, Antimicrobial, and Antidiabetic Applications.
Aldughaylibi, Fatimah Saeed; Raza, Muhammad Asam; Naeem, Sumaira; Rafi, Humera; Alam, Mir Waqas; Souayeh, Basma; Farhan, Mohd; Aamir, Muhammad; Zaidi, Noushi; Mir, Tanveer Ahmad.
Afiliación
  • Aldughaylibi FS; Department of Physics, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
  • Raza MA; Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.
  • Naeem S; Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.
  • Rafi H; Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.
  • Alam MW; Department of Physics, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
  • Souayeh B; Department of Physics, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
  • Farhan M; Department of Basic Sciences, Preparatory Year Deanship, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
  • Aamir M; Department of Basic Sciences, Preparatory Year Deanship, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
  • Zaidi N; Department of Basic Sciences, Preparatory Year Deanship, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
  • Mir TA; Laboratory of Tissue/Organ Bioengineering and BioMEMS, Organ Transplant Centre of Excellence, Transplantation Research & Innovation (Dpt)-R, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia.
Molecules ; 27(18)2022 Sep 13.
Article en En | MEDLINE | ID: mdl-36144671
ABSTRACT
This study was designed to check the potential of secondary metabolites of the selected plants; Citrullus colocynthis, Solanum nigrum, Solanum surattense, Calotropis procera, Agave americana, and Anagallis arvensis for antioxidant, antibacterial, antifungal, and antidiabetic agents. Plant material was soaked in ethanol/methanol to get the crude extract, which was further partitioned via solvent extraction technique. GCMS and FTIR analytical techniques were applied to check the compounds responsible for causing antioxidant, antimicrobial, and antidiabetic activities. It was concluded that about 80% of studied extracts/fractions were active against α-amylase, ranging from 43 to 96%. The highest activity (96.63%) was exhibited by butanol fractions of A. arvensis while the least response (43.65%) was shown by the aqueous fraction of C. colocynthis and the methanol fraction of fruit of S. surattense. The highest antioxidant activity was shown by the ethyl acetate fraction of Anagallis arvensis (78.1%), while aqueous as well as n-hexane fractions are the least active throughout the assay. Results showed that all tested plants can be an excellent source of natural products with potential antimicrobial, antioxidant, and antidiabetic potential. The biological response of these species is depicted as a good therapeutic agent, and, in the future, it can be encapsulated for drug discovery.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antiinfecciosos / Antioxidantes Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Arabia Saudita

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antiinfecciosos / Antioxidantes Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Arabia Saudita