CD73 activity of mesenchymal stromal cell-derived extracellular vesicle preparations is detergent-resistant and does not correlate with immunomodulatory capabilities.

Bauer, Fabiola Nardi; Tertel, Tobias; Stambouli, Oumaima; Wang, Chen; Dittrich, Robin; Staubach, Simon; Börger, Verena; Hermann, Dirk M; Brandau, Sven; Giebel, Bernd

Bauer, Fabiola Nardi; Tertel, Tobias; Stambouli, Oumaima; Wang, Chen; Dittrich, Robin; Staubach, Simon; Börger, Verena; Hermann, Dirk M; Brandau, Sven; Giebel, Bernd.

Afiliación

Bauer FN; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Tertel T; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Stambouli O; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Wang C; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Dittrich R; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Staubach S; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Börger V; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Hermann DM; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Brandau S; Department of Otorhinolaryngology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Giebel B; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. Electronic address: bernd.giebel@uk-essen.de.

Cytotherapy ; 25(2): 138-147, 2023 02.

Article en En | MEDLINE | ID: mdl-36244910

Asunto(s)

5'-Nucleotidasa; Vesículas Extracelulares; Enfermedad Injerto contra Huésped; Células Madre Mesenquimatosas; Animales; Humanos; Ratones; 5'-Nucleotidasa/inmunología; 5'-Nucleotidasa/metabolismo; Detergentes/química; Vesículas Extracelulares/metabolismo; Enfermedad Injerto contra Huésped/terapia; Inmunomodulación/fisiología; Células Madre Mesenquimatosas/metabolismo

Palabras clave

AMP; CD73 activity; ecto-5'-nucleotidase; extracellular vesicles; mesenchymal stromal cells; potency assay

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: 5'-Nucleotidasa / Células Madre Mesenquimatosas / Vesículas Extracelulares / Enfermedad Injerto contra Huésped Límite: Animals / Humans Idioma: En Revista: Cytotherapy Asunto de la revista: TERAPEUTICA Año: 2023 Tipo del documento: Article País de afiliación: Alemania

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