The Use of the International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy.
Am J Clin Pathol
; 159(2): 138-145, 2023 02 01.
Article
en En
| MEDLINE
| ID: mdl-36370120
ABSTRACT
OBJECTIVES:
To perform the first meta-analysis regarding the pooled risk of malignancy (ROM) of each category of the Yokohama system for reporting breast fine-needle aspiration, as well as assess the latter's diagnostic accuracy using this new system.METHODS:
Two databases were searched, followed by data extraction, study quality assessment, and statistical analysis.RESULTS:
The "Insufficient," "Benign," "Atypical," "Suspicious," and "Malignant" Yokohama system categories were associated with a pooled ROM of 17% (95% CI, 10%-28%), 1% (95% CI, 1%-3%), 20% (95% CI, 17%-23%), 86% (95% CI, 79%-92%), and 100% (95% CI, 99%-100%), respectively. When both "Suspicious" and "Malignant" interpretations were regarded as cytologically positive, sensitivity (SN) was 91% (95% CI, 87.6%-93.5%) and false-positive rate (FPR) was 2.33% (95% CI, 1.30-4.14%). A summary receiver operating characteristic curve was constructed and the pooled area under the curve was 97.3%, while the pooled diagnostic odds ratio was 564 (95% CI, 264-1,206), indicating a high level of diagnostic accuracy. When only "Malignant" interpretations were regarded as cytologically positive, the pooled FPR was lower (0.75%; 95% CI, .39%-1.42%) but at the expense of SN (76.61%; 95% CI, 70.05%-82.10%).CONCLUSIONS:
Despite Yokohama's system early success, more data would be needed to unravel the system's value in clinical practice.Palabras clave
Texto completo:
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Banco de datos:
MEDLINE
Asunto principal:
Mama
/
Citodiagnóstico
Tipo de estudio:
Prognostic_studies
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Am J Clin Pathol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Chipre