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Population pharmacokinetic modelling of tremelimumab in patients with advanced solid tumours and the impact of disease status on time-varying clearance.
Hwang, Michael; Chia, Yen Lin; Zheng, Yanan; Chen, Cecil Chi-Keung; He, Jimmy; Song, Xuyang; Zhou, Diansong; Goldberg, Sarah B; Siu, Lillian L; Planchard, David; Peters, Solange; Mann, Helen; Krug, Lee; Even, Caroline.
Afiliación
  • Hwang M; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, South San Francisco, CA, USA.
  • Chia YL; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, South San Francisco, CA, USA.
  • Zheng Y; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, South San Francisco, CA, USA.
  • Chen CC; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, South San Francisco, CA, USA.
  • He J; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
  • Song X; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
  • Zhou D; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Boston, MA, USA.
  • Goldberg SB; Department of Medicine (Section of Medical Oncology), Yale School of Medicine, New Haven, CT, USA.
  • Siu LL; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Planchard D; Department of Medical Oncology, Thoracic Unit, Institut Gustave-Roussy, Villejuif, France.
  • Peters S; Department of Oncology CHUV-UNIL, University Hospital Lausanne, Lausanne, Switzerland.
  • Mann H; Oncology Biometrics, Oncology R&D, AstraZeneca, Cambridge, UK.
  • Krug L; Late Development Oncology R&D, AstraZeneca, Gaithersburg, MD, USA.
  • Even C; Head and Neck Department, Institut Gustave-Roussy, Villejuif, France.
Br J Clin Pharmacol ; 89(5): 1601-1616, 2023 05.
Article en En | MEDLINE | ID: mdl-36454221
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Límite: Adult / Humans Idioma: En Revista: Br J Clin Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Límite: Adult / Humans Idioma: En Revista: Br J Clin Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos