Procyanidins Extracted from the Lotus Seedpod Ameliorate Cognitive Impairment through CREB-BDNF Pathway Mediated LTP in <i>APP/PS1</i> Transgenic Mice.

Wang, Ziping; Li, Xiaolong; Ren, Xiaotong; Zhao, Siqi; Chen, Wenwen; Fan, Cheng; Xu, Yangliu; Pi, Xuejiao; Zhang, Yidan; Wang, Ting; Rong, Shuang

Procyanidins Extracted from the Lotus Seedpod Ameliorate Cognitive Impairment through CREB-BDNF Pathway Mediated LTP in APP/PS1 Transgenic Mice.

Wang, Ziping; Li, Xiaolong; Ren, Xiaotong; Zhao, Siqi; Chen, Wenwen; Fan, Cheng; Xu, Yangliu; Pi, Xuejiao; Zhang, Yidan; Wang, Ting; Rong, Shuang.

Afiliación

Wang Z; Department of Nutrition Hygiene and Toxicology, Academy of Nutrition and Health, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Wuhan University of Science and Technology, Wuhan, 430065, China.
Li X; Department of Neurology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, 441100, China.
Ren X; Department of Public Health, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, China.
Zhao S; Department of Chronic Disease, Wuhan Center for Disease Control and Prevention, Wuhan, 430015, China.
Chen W; Department of Biology, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, China.
Fan C; Department of Pharmacy, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, China.
Xu Y; Department of Nutrition Hygiene and Toxicology, Academy of Nutrition and Health, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Wuhan University of Science and Technology, Wuhan, 430065, China.
Pi X; Department of Pharmacy, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, China.
Zhang Y; Department of Nutrition Hygiene and Toxicology, Academy of Nutrition and Health, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Wuhan University of Science and Technology, Wuhan, 430065, China.
Wang T; Department of Nutrition Hygiene and Toxicology, Academy of Nutrition and Health, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Wuhan University of Science and Technology, Wuhan, 430065, China.
Rong S; Department of Pharmacy, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, China.

Curr Pharm Biotechnol ; 24(12): 1560-1567, 2023.

Article en En | MEDLINE | ID: mdl-36757040

Asunto(s)

Enfermedad de Alzheimer; Disfunción Cognitiva; Lotus; Enfermedades Neurodegenerativas; Proantocianidinas; Ratones; Animales; Ratones Transgénicos; Potenciación a Largo Plazo; Péptidos beta-Amiloides/metabolismo; Factor Neurotrófico Derivado del Encéfalo/genética; Factor Neurotrófico Derivado del Encéfalo/metabolismo; Factor Neurotrófico Derivado del Encéfalo/farmacología; Proantocianidinas/farmacología; Proantocianidinas/uso terapéutico; Proantocianidinas/metabolismo; Lotus/metabolismo; Enfermedad de Alzheimer/tratamiento farmacológico; Enfermedad de Alzheimer/metabolismo; Disfunción Cognitiva/tratamiento farmacológico; Semillas; Precursor de Proteína beta-Amiloide/genética; Precursor de Proteína beta-Amiloide/metabolismo; Precursor de Proteína beta-Amiloide/farmacología; Modelos Animales de Enfermedad; Aprendizaje por Laberinto; Hipocampo

Palabras clave

<i>APP/PS1</i>; Alzheimer's disease; amyloid ß; cognitive impairment; long-term potentiation; procyanidins from lotus seedpod; transgenic mice

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Neurodegenerativas / Proantocianidinas / Enfermedad de Alzheimer / Disfunción Cognitiva / Lotus Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Curr Pharm Biotechnol Asunto de la revista: BIOTECNOLOGIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China

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