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Comprehensive molecular phenotyping of ARID1A-deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities.
Xu, Chang; Huang, Kie Kyon; Law, Jia Hao; Chua, Joy Shijia; Sheng, Taotao; Flores, Natasha M; Pizzi, Melissa Pool; Okabe, Atsushi; Tan, Angie Lay Keng; Zhu, Feng; Kumar, Vikrant; Lu, Xiaoyin; Benitez, Ana Morales; Lian, Benedict Shi Xiang; Ma, Haoran; Ho, Shamaine Wei Ting; Ramnarayanan, Kalpana; Anene-Nzelu, Chukwuemeka George; Razavi-Mohseni, Milad; Abdul Ghani, Siti Aishah Binte; Tay, Su Ting; Ong, Xuewen; Lee, Ming Hui; Guo, Yu Amanda; Ashktorab, Hassan; Smoot, Duane; Li, Shang; Skanderup, Anders Jacobsen; Beer, Michael A; Foo, Roger Sik Yin; Wong, Joel Shi Hao; Sanghvi, Kaushal; Yong, Wei Peng; Sundar, Raghav; Kaneda, Atsushi; Prabhakar, Shyam; Mazur, Pawel Karol; Ajani, Jaffer A; Yeoh, Khay Guan; So, Jimmy Bok-Yan; Tan, Patrick.
Afiliación
  • Xu C; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore gmstanp@duke-nus.edu.sg sursbyj@nus.edu.sg chang.xu@duke-nus.edu.sg.
  • Huang KK; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Law JH; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Chua JS; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Sheng T; Epigenetic and Epigenomic Regulation, Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore.
  • Flores NM; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Pizzi MP; Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Okabe A; Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Tan ALK; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Zhu F; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Kumar V; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Lu X; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Benitez AM; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Lian BSX; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Ma H; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Ho SWT; Epigenetic and Epigenomic Regulation, Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore.
  • Ramnarayanan K; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Anene-Nzelu CG; Cardiovascular Research Institute, National University Health System, Singapore.
  • Razavi-Mohseni M; Human Genetics, Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore.
  • Abdul Ghani SAB; Montreal Heart Institute, Quebec, Québec, Canada.
  • Tay ST; Department of Medicine, University of Montreal, Quebec, Québec, Canada.
  • Ong X; Department of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Baltimore, Maryland, USA.
  • Lee MH; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Guo YA; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Ashktorab H; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Smoot D; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Li S; Computational and Systems Biology, Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore.
  • Skanderup AJ; Department of Medicine, Howard University, Washington, DC, USA.
  • Beer MA; Department of Internal Medicine, Meharry Medical College, Nashville, Tennessee, USA.
  • Foo RSY; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Wong JSH; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Sanghvi K; Computational and Systems Biology, Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore.
  • Yong WP; Department of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Baltimore, Maryland, USA.
  • Sundar R; Cardiovascular Research Institute, National University Health System, Singapore.
  • Kaneda A; Human Genetics, Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore.
  • Prabhakar S; Department of General Surgery, Tan Tock Seng Hospital, Singapore.
  • Mazur PK; Department of General Surgery, Tan Tock Seng Hospital, Singapore.
  • Ajani JA; Department of Haematology-Oncology, National University Health System, Singapore.
  • Yeoh KG; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
  • So JB; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
  • Tan P; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Gut ; 72(9): 1651-1663, 2023 09.
Article en En | MEDLINE | ID: mdl-36918265
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Factores de Transcripción Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Gut Año: 2023 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Factores de Transcripción Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Gut Año: 2023 Tipo del documento: Article