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RyR2 inhibition with dantrolene is antiarrhythmic, prevents further pathological remodeling, and improves cardiac function in chronic ischemic heart disease.
Schmeckpeper, Jeffrey; Kim, Kyungsoo; George, Sharon A; Blackwell, Daniel J; Brennan, Jaclyn A; Efimov, Igor R; Knollmann, Bjorn C.
Afiliación
  • Schmeckpeper J; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Kim K; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • George SA; Department of Biomedical Engineering, the George Washington University, Washington DC, USA; Department of Biomedical Engineering, Northwestern University, Chicago, IL, USA.
  • Blackwell DJ; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Brennan JA; Department of Biomedical Engineering, the George Washington University, Washington DC, USA.
  • Efimov IR; Department of Biomedical Engineering, the George Washington University, Washington DC, USA; Department of Biomedical Engineering, Northwestern University, Chicago, IL, USA.
  • Knollmann BC; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: bjorn.knollmann@vanderbilt.edu.
J Mol Cell Cardiol ; 181: 67-78, 2023 08.
Article en En | MEDLINE | ID: mdl-37285929
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Taquicardia Ventricular / Isquemia Miocárdica Tipo de estudio: Clinical_trials / Etiology_studies Límite: Animals Idioma: En Revista: J Mol Cell Cardiol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Taquicardia Ventricular / Isquemia Miocárdica Tipo de estudio: Clinical_trials / Etiology_studies Límite: Animals Idioma: En Revista: J Mol Cell Cardiol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos