Human Osteoarthritic Chondrocytes Express Nineteen Different TRP-Genes-TRPA1 and TRPM8 as Potential Drug Targets.

Halonen, Leevi; Pemmari, Antti; Nummenmaa, Elina; Hämäläinen, Mari; Moilanen, Teemu; Vuolteenaho, Katriina; Moilanen, Eeva

Halonen, Leevi; Pemmari, Antti; Nummenmaa, Elina; Hämäläinen, Mari; Moilanen, Teemu; Vuolteenaho, Katriina; Moilanen, Eeva.

Afiliación

Halonen L; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Pemmari A; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Nummenmaa E; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Hämäläinen M; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Moilanen T; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Vuolteenaho K; Coxa Hospital for Joint Replacement, 33520 Tampere, Finland.
Moilanen E; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.

Int J Mol Sci ; 24(12)2023 Jun 13.

Article en En | MEDLINE | ID: mdl-37373205

Asunto(s)

Canales Catiónicos TRPM; Canales de Potencial de Receptor Transitorio; Humanos; Canales Catiónicos TRPM/metabolismo; Canales Catiónicos TRPV/genética; Canales Catiónicos TRPV/metabolismo; Mentol/farmacología; Condrocitos/metabolismo; Canal Catiónico TRPA1/genética; Canal Catiónico TRPA1/metabolismo; Canales de Potencial de Receptor Transitorio/genética; Dolor/metabolismo; Dexametasona/farmacología; Dexametasona/metabolismo; Proteínas Serina-Treonina Quinasas/metabolismo; Proteínas de la Membrana/metabolismo

Palabras clave

TPR ion channel; TRPA1; TRPM8; chondrocyte; glucocorticoid; menthol; non-steroidal anti-inflammatory drug; osteoarthritis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Canales de Potencial de Receptor Transitorio / Canales Catiónicos TRPM Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Finlandia

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