Early chromosome condensation by XIST builds A-repeat RNA density that facilitates gene silencing.

Valledor, Melvys; Byron, Meg; Dumas, Brett; Carone, Dawn M; Hall, Lisa L; Lawrence, Jeanne B

Valledor, Melvys; Byron, Meg; Dumas, Brett; Carone, Dawn M; Hall, Lisa L; Lawrence, Jeanne B.

Afiliación

Valledor M; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.
Byron M; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.
Dumas B; Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA.
Carone DM; Department of Biology, Swarthmore College, Swarthmore, PA 19081, USA.
Hall LL; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA. Electronic address: lisa.hall@umassmed.edu.
Lawrence JB; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA; Department of Pediatrics, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA. Electronic address: jeanne.lawrence@umassmed.edu.

Cell Rep ; 42(7): 112686, 2023 07 25.

Article en En | MEDLINE | ID: mdl-37384527

Asunto(s)

ARN Largo no Codificante; Inactivación del Cromosoma X; Humanos; ARN Largo no Codificante/genética; ARN Largo no Codificante/metabolismo; Cromatina; Silenciador del Gen; Cromosoma X/metabolismo

Palabras clave

A-Repeat; Barr body; CIZ1; CP: Molecular biology; CP: Stem cell research; H3K27; UbH2A; XIST; chromosome structure; epigenetics; heterochromatin; transcription

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inactivación del Cromosoma X / ARN Largo no Codificante Límite: Humans Idioma: En Revista: Cell Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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