TMBIM6 deficiency leads to bone loss by accelerating osteoclastogenesis.

Yi, Sun-Ju; Jang, You-Jee; Lee, Seokchan; Cho, Sung-Jin; Kang, Kyuho; Park, Jae-Il; Chae, Han-Jung; Kim, Hyung-Ryong; Kim, Kyunghwan

Yi, Sun-Ju; Jang, You-Jee; Lee, Seokchan; Cho, Sung-Jin; Kang, Kyuho; Park, Jae-Il; Chae, Han-Jung; Kim, Hyung-Ryong; Kim, Kyunghwan.

Afiliación

Yi SJ; Department of Biological Sciences and Biotechnology, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea.
Jang YJ; Department of Biomedical Laboratory Science, Honam University, Gwangju, Republic of Korea.
Lee S; Department of Biological Sciences and Biotechnology, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea.
Cho SJ; Department of Biological Sciences and Biotechnology, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea.
Kang K; Department of Biological Sciences and Biotechnology, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea.
Park JI; Korea Basic Science Institute, Gwangju Center at Chonnam National University, Gwangju, Republic of Korea.
Chae HJ; School of Pharmacy and New Drug Development Research Institute, Jeonbuk National University, Jeonju, Republic of Korea.
Kim HR; Department of Pharmacology, College of Dentistry, Jeonbuk National University, Jeonju, Republic of Korea.
Kim K; Department of Biological Sciences and Biotechnology, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea. Electronic address: kyungkim@chungbuk.ac.kr.

Redox Biol ; 64: 102804, 2023 08.

Article en En | MEDLINE | ID: mdl-37399733

Asunto(s)

Resorción Ósea; Proteínas de la Membrana; Osteoclastos; Osteogénesis; Animales; Masculino; Ratones; Resorción Ósea/genética; Diferenciación Celular; Proteínas de la Membrana/genética; Ratones Endogámicos C57BL; Ratones Noqueados; Osteoclastos/citología; Ligando RANK/metabolismo; Transducción de Señal; Factor de Transcripción ReIA/metabolismo; Oxidación-Reducción

Palabras clave

Bone development; Osteoclastogenesis; Reactive oxygen species; TMBIM6; p65

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteoclastos / Osteogénesis / Resorción Ósea / Proteínas de la Membrana Límite: Animals Idioma: En Revista: Redox Biol Año: 2023 Tipo del documento: Article

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