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Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands.
van der Plas, Johan L; Kuiper, Vincent P; Bagchus, Wilhelmina M; Bödding, Matthias; Yalkinoglu, Özkan; Tappert, Aliona; Seitzinger, Andrea; Spangenberg, Thomas; Bezuidenhout, Deon; Wilkins, Justin; Oeuvray, Claude; Dhingra, Satish K; Thathy, Vandana; Fidock, David A; Smidt, Lisanne C A; Roozen, Geert V T; Koopman, Jan Pieter R; Lamers, Olivia A C; Sijtsma, Jeroen; van Schuijlenburg, Roos; Wessels, Els; Meij, Pauline; Kamerling, Ingrid M C; Roestenberg, Meta; Khandelwal, Akash.
Afiliación
  • van der Plas JL; Centre for Human Drug Research, Leiden, Netherlands; Department of Infectious Diseases and Parasitology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • Kuiper VP; Department of Infectious Diseases and Parasitology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • Bagchus WM; Merck Institute for Pharmacometrics, Merck Serono (an affiliate of Merck KGaA, Darmstadt, Germany), Lausanne, Switzerland.
  • Bödding M; The healthcare business of Merck KGaA, Darmstadt, Germany.
  • Yalkinoglu Ö; The healthcare business of Merck KGaA, Darmstadt, Germany.
  • Tappert A; The healthcare business of Merck KGaA, Darmstadt, Germany.
  • Seitzinger A; The healthcare business of Merck KGaA, Darmstadt, Germany.
  • Spangenberg T; Global Health Institute of Merck, Ares Trading (a subsidiary of Merck KGaA, Darmstadt, Germany), Eysins, Switzerland.
  • Bezuidenhout D; Merck (Pty) (an affiliate of Merck KGaA, Darmstadt, Germany), Modderfontein, South Africa.
  • Wilkins J; Occams, Amstelveen, Netherlands.
  • Oeuvray C; Global Health Institute of Merck, Ares Trading (a subsidiary of Merck KGaA, Darmstadt, Germany), Eysins, Switzerland.
  • Dhingra SK; Hemogenyx Pharmaceuticals, New York, NY, USA.
  • Thathy V; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY, USA.
  • Fidock DA; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY, USA; Center for Malaria Therapeutics and Antimicrobial Resistance, Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
  • Smidt LCA; Centre for Human Drug Research, Leiden, Netherlands.
  • Roozen GVT; Department of Infectious Diseases and Parasitology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • Koopman JPR; Department of Infectious Diseases and Parasitology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • Lamers OAC; Department of Infectious Diseases and Parasitology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • Sijtsma J; Department of Infectious Diseases and Parasitology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • van Schuijlenburg R; Department of Infectious Diseases and Parasitology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • Wessels E; Department of Medical Microbiology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • Meij P; Center for Cell and Gene Therapy, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • Kamerling IMC; Centre for Human Drug Research, Leiden, Netherlands; Department of Infectious Diseases and Parasitology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
  • Roestenberg M; Department of Infectious Diseases and Parasitology, Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands. Electronic address: m.roestenberg@lumc.nl.
  • Khandelwal A; The healthcare business of Merck KGaA, Darmstadt, Germany.
Lancet Infect Dis ; 23(10): 1164-1174, 2023 10.
Article en En | MEDLINE | ID: mdl-37414066

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Malaria Falciparum / Antimaláricos Tipo de estudio: Clinical_trials / Guideline / Prognostic_studies Límite: Adult / Humans País/Región como asunto: Europa Idioma: En Revista: Lancet Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Malaria Falciparum / Antimaláricos Tipo de estudio: Clinical_trials / Guideline / Prognostic_studies Límite: Adult / Humans País/Región como asunto: Europa Idioma: En Revista: Lancet Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos