Enhancing the functional maturity of hiPSC-derived cardiomyocytes to assess inotropic compounds.

Zhang, Xiaoyu; Aggarwal, Praful; Broeckel, Ulrich; Abassi, Yama A

Zhang, Xiaoyu; Aggarwal, Praful; Broeckel, Ulrich; Abassi, Yama A.

Afiliación

Zhang X; Agilent Technologies, San Diego, CA 92121, USA. Electronic address: xiaoyu.zhang@agilent.com.
Aggarwal P; Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address: paggarwal@mcw.edu.
Broeckel U; Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address: ubroeckel@mcw.edu.
Abassi YA; Agilent Technologies, San Diego, CA 92121, USA. Electronic address: yama.abassi@agilent.com.

J Pharmacol Toxicol Methods ; 123: 107282, 2023.

Article en En | MEDLINE | ID: mdl-37419294

Asunto(s)

Células Madre Pluripotentes Inducidas; Miocitos Cardíacos; Humanos; Miocitos Cardíacos/fisiología; Células Madre Pluripotentes Inducidas/fisiología; Calcio/metabolismo; Diferenciación Celular; Células Cultivadas

Palabras clave

Contractility; Electrical pacing; Functional maturation; Impedance; Inotrope; Real-time measurement; hiPSC cardiomyocyte

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Miocitos Cardíacos / Células Madre Pluripotentes Inducidas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Pharmacol Toxicol Methods Asunto de la revista: FARMACOLOGIA / TOXICOLOGIA Año: 2023 Tipo del documento: Article

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