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An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate.
Hansen, Stine L; Larsen, Hjalte L; Pikkupeura, Laura M; Maciag, Grzegorz; Guiu, Jordi; Müller, Iris; Clement, Ditte L; Mueller, Christina; Johansen, Jens Vilstrup; Helin, Kristian; Lerdrup, Mads; Jensen, Kim B.
Afiliación
  • Hansen SL; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
  • Larsen HL; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
  • Pikkupeura LM; Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen N, Denmark.
  • Maciag G; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
  • Guiu J; Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen N, Denmark.
  • Müller I; Institut d'Investigació Biomèdica de Bellvitge-IDIBELL, 3a planta, Av. Granvia de l'Hospitalet 199, 08908 Hospitalet de Llobregat, Spain.
  • Clement DL; Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen N, Denmark.
  • Mueller C; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
  • Johansen JV; Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen N, Denmark.
  • Helin K; Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen N, Denmark.
  • Lerdrup M; Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen N, Denmark.
  • Jensen KB; The DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Sci Adv ; 9(28): eadg4055, 2023 07 14.
Article en En | MEDLINE | ID: mdl-37436979

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Adultas / Sistemas CRISPR-Cas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Adv Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Adultas / Sistemas CRISPR-Cas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Adv Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca