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Catalytic spike antibodies: A new paradigm in neutralization.
McNamara, Ryan P.
Afiliación
  • McNamara RP; Ragon Institute of Mass General, MIT, and Harvard, 400 Technology Square, Cambridge, MA 02139, USA. Electronic address: rpmcnamara@mgh.harvard.edu.
Cell Chem Biol ; 30(7): 701-702, 2023 07 20.
Article en En | MEDLINE | ID: mdl-37478826
In this issue, McConnell et al.10 demonstrate that COVID-19 convalescent plasma (CCP)-derived antibodies can neutralize SARS-CoV-2 by proteolytically cleaving the spike protein. The CCP antibody-mediated catalysis has broader implications beyond COVID-19 and can be applicable in understanding the mechanism of antibody-based neutralization of different pathogens.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Anticuerpos Catalíticos / COVID-19 Límite: Humans Idioma: En Revista: Cell Chem Biol Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Anticuerpos Catalíticos / COVID-19 Límite: Humans Idioma: En Revista: Cell Chem Biol Año: 2023 Tipo del documento: Article