Regulatory role of Chitinase 3-like 1 gene in papillary thyroid carcinoma proved by integration analyses of single-cell sequencing with cohort and experimental validations.

Zhang, Xiaojun; Peng, Wanwan; Fan, Jie; Luo, Ruihua; Liu, Shanting; Du, Wei; Luo, Chaochao; Zheng, Jiawen; Pan, Xinghua; Ge, Hong

Zhang, Xiaojun; Peng, Wanwan; Fan, Jie; Luo, Ruihua; Liu, Shanting; Du, Wei; Luo, Chaochao; Zheng, Jiawen; Pan, Xinghua; Ge, Hong.

Afiliación

Zhang X; Department of Head Neck and Thyroid Surgery, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, 450008, Zhengzhou, China.
Peng W; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Southern Medical University, 510515, Guangzhou, China.
Fan J; Department of Head Neck and Thyroid Surgery, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, 450008, Zhengzhou, China.
Luo R; Department of Head Neck and Thyroid Surgery, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, 450008, Zhengzhou, China.
Liu S; Department of Head Neck and Thyroid Surgery, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, 450008, Zhengzhou, China.
Du W; Department of Head Neck and Thyroid Surgery, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, 450008, Zhengzhou, China.
Luo C; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Southern Medical University, 510515, Guangzhou, China.
Zheng J; Department of Molecular Pathology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, 450008, Zhengzhou, China.
Pan X; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Southern Medical University, 510515, Guangzhou, China. panvictor@smu.edu.cn.
Ge H; Department of Pediatrics, Nanfang Hospital, Southern Medical University, 510515, Guangzhou, China. panvictor@smu.edu.cn.

Cancer Cell Int ; 23(1): 145, 2023 Jul 21.

Article en En | MEDLINE | ID: mdl-37480002

Palabras clave

CHI3L1; Invasion and metastasis; Papillary thyroid carcinoma; Single-cell RNA sequencing; Subpopulation

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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Cancer Cell Int Año: 2023 Tipo del documento: Article País de afiliación: China

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