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Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
Venneti, Sriram; Kawakibi, Abed Rahman; Ji, Sunjong; Waszak, Sebastian M; Sweha, Stefan R; Mota, Mateus; Pun, Matthew; Deogharkar, Akash; Chung, Chan; Tarapore, Rohinton S; Ramage, Samuel; Chi, Andrew; Wen, Patrick Y; Arrillaga-Romany, Isabel; Batchelor, Tracy T; Butowski, Nicholas A; Sumrall, Ashley; Shonka, Nicole; Harrison, Rebecca A; de Groot, John; Mehta, Minesh; Hall, Matthew D; Daghistani, Doured; Cloughesy, Timothy F; Ellingson, Benjamin M; Beccaria, Kevin; Varlet, Pascale; Kim, Michelle M; Umemura, Yoshie; Garton, Hugh; Franson, Andrea; Schwartz, Jonathan; Jain, Rajan; Kachman, Maureen; Baum, Heidi; Burant, Charles F; Mottl, Sophie L; Cartaxo, Rodrigo T; John, Vishal; Messinger, Dana; Qin, Tingting; Peterson, Erik; Sajjakulnukit, Peter; Ravi, Karthik; Waugh, Alyssa; Walling, Dustin; Ding, Yujie; Xia, Ziyun; Schwendeman, Anna; Hawes, Debra.
Afiliación
  • Venneti S; University of Michigan, Ann Arbor, Michigan.
  • Kawakibi AR; University of Michigan, Ann Arbor, Michigan.
  • Ji S; University of Michigan, Ann Arbor, Michigan.
  • Waszak SM; University of California, San Francisco, San Francisco, California.
  • Sweha SR; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway.
  • Mota M; Laboratory of Computational Neuro-Oncology, Swiss Institute for Experimental Cancer Research, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
  • Pun M; University of Michigan, Ann Arbor, Michigan.
  • Deogharkar A; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Chung C; University of Michigan, Ann Arbor, Michigan.
  • Tarapore RS; University of Michigan, Ann Arbor, Michigan.
  • Ramage S; University of Michigan, Ann Arbor, Michigan.
  • Chi A; University of Michigan, Ann Arbor, Michigan.
  • Wen PY; Department of New Biology, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea.
  • Arrillaga-Romany I; Chimerix, Inc., Durham, North Carolina.
  • Batchelor TT; Chimerix, Inc., Durham, North Carolina.
  • Butowski NA; NYU Langone Health, New York, New York.
  • Sumrall A; Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts.
  • Shonka N; Massachusetts General Hospital, Boston, Massachusetts.
  • Harrison RA; Brigham and Women's Hospital, Boston, Massachusetts.
  • de Groot J; University of California, San Francisco, San Francisco, California.
  • Mehta M; Levine Cancer Institute, Charlotte, North Carolina.
  • Hall MD; Mayo Clinic, Rochester, Minnesota.
  • Daghistani D; BC Cancer, The University of British Columbia, Vancouver, BC, Canada.
  • Cloughesy TF; University of California, San Francisco, San Francisco, California.
  • Ellingson BM; Miami Cancer Institute, Miami, Florida.
  • Beccaria K; Miami Cancer Institute, Miami, Florida.
  • Varlet P; Miami Cancer Institute, Miami, Florida.
  • Kim MM; University of California, Los Angeles, Los Angeles, California.
  • Umemura Y; University of California, Los Angeles, Los Angeles, California.
  • Garton H; Department of Neurosurgery, Necker Sick Children's University Hospital and Paris Descartes University, Paris, France.
  • Franson A; Department of Neuropathology, Sainte-Anne Hospital and Paris Descartes University, Paris, France.
  • Schwartz J; University of Michigan, Ann Arbor, Michigan.
  • Jain R; University of Michigan, Ann Arbor, Michigan.
  • Kachman M; University of Michigan, Ann Arbor, Michigan.
  • Baum H; University of Michigan, Ann Arbor, Michigan.
  • Burant CF; Mayo Clinic, Rochester, Minnesota.
  • Mottl SL; NYU Langone Health, New York, New York.
  • Cartaxo RT; University of Michigan, Ann Arbor, Michigan.
  • John V; University of Michigan, Ann Arbor, Michigan.
  • Messinger D; University of Michigan, Ann Arbor, Michigan.
  • Qin T; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway.
  • Peterson E; University of Michigan, Ann Arbor, Michigan.
  • Sajjakulnukit P; University of Michigan, Ann Arbor, Michigan.
  • Ravi K; University of Michigan, Ann Arbor, Michigan.
  • Waugh A; University of Michigan, Ann Arbor, Michigan.
  • Walling D; University of Michigan, Ann Arbor, Michigan.
  • Ding Y; University of Michigan, Ann Arbor, Michigan.
  • Xia Z; University of Michigan, Ann Arbor, Michigan.
  • Schwendeman A; University of Michigan, Ann Arbor, Michigan.
  • Hawes D; University of Michigan, Ann Arbor, Michigan.
Cancer Discov ; 13(11): 2370-2393, 2023 11 01.
Article en En | MEDLINE | ID: mdl-37584601
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioma Límite: Humans Idioma: En Revista: Cancer Discov Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioma Límite: Humans Idioma: En Revista: Cancer Discov Año: 2023 Tipo del documento: Article