Pioneer activity distinguishes activating from non-activating SOX2 binding sites.

Maresca, Michela; van den Brand, Teun; Li, Hangpeng; Teunissen, Hans; Davies, James; de Wit, Elzo

Maresca, Michela; van den Brand, Teun; Li, Hangpeng; Teunissen, Hans; Davies, James; de Wit, Elzo.

Afiliación

Maresca M; Division of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
van den Brand T; Division of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Li H; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Teunissen H; Division of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Davies J; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
de Wit E; Division of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

EMBO J ; 42(20): e113150, 2023 10 16.

Article en En | MEDLINE | ID: mdl-37691488

Asunto(s)

Cromatina; Factores de Transcripción SOXB1; Factores de Transcripción; Sitios de Unión; Cromatina/genética; Regulación de la Expresión Génica; Unión Proteica; Factores de Transcripción/metabolismo; Factores de Transcripción SOXB1/genética; Factores de Transcripción SOXB1/metabolismo; Células Madre Embrionarias de Ratones/metabolismo; Animales; Ratones

Palabras clave

acute protein depletion; chromatin accessibility; gene regulation; pioneer activity; transcription factors

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Cromatina / Factores de Transcripción SOXB1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: EMBO J Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos

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