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Synechococcus elongatus Argonaute reduces natural transformation efficiency and provides immunity against exogenous plasmids.
Taton, Arnaud; Gilderman, Tami S; Ernst, Dustin C; Omaga, Carla A; Cohen, Lucas A; Rey-Bedon, Camilo; Golden, James W; Golden, Susan S.
Afiliación
  • Taton A; School of Biological Sciences, University of California, San Diego , La Jolla, California, USA.
  • Gilderman TS; School of Biological Sciences, University of California, San Diego , La Jolla, California, USA.
  • Ernst DC; Center for Circadian Biology, University of California, San Diego , La Jolla, California, USA.
  • Omaga CA; Center for Circadian Biology, University of California, San Diego , La Jolla, California, USA.
  • Cohen LA; School of Biological Sciences, University of California, San Diego , La Jolla, California, USA.
  • Rey-Bedon C; School of Biological Sciences, University of California, San Diego , La Jolla, California, USA.
  • Golden JW; School of Biological Sciences, University of California, San Diego , La Jolla, California, USA.
  • Golden SS; School of Biological Sciences, University of California, San Diego , La Jolla, California, USA.
mBio ; 14(5): e0184323, 2023 Oct 31.
Article en En | MEDLINE | ID: mdl-37791787
ABSTRACT
IMPORTANCE S. elongatus is an important cyanobacterial model organism for the study of its prokaryotic circadian clock, photosynthesis, and other biological processes. It is also widely used for genetic engineering to produce renewable biochemicals. Our findings reveal an SeAgo-based defense mechanism in S. elongatus against the horizontal transfer of genetic material. We demonstrate that deletion of the ago gene facilitates genetic studies and genetic engineering of S. elongatus.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Synechococcus / Relojes Circadianos Tipo de estudio: Prognostic_studies Idioma: En Revista: MBio Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Synechococcus / Relojes Circadianos Tipo de estudio: Prognostic_studies Idioma: En Revista: MBio Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos